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New frontiers for Vapourtec with chinese collaboration

Date: 14 May 2015 | Category: News

Vapourtec (Cambridge, UK) have announced a research collaboration with Professor Pengfei Li of the Frontier Institute of Science and Technology (FIST) at Xi’an Jiaotong University in China to develop novel, continuous flow, photochemical reactions using Vapourtec’s easy-Photochem…

Graduate-appointment

Vapourtec expands research & development team

Date: 06 May 2015 | Category: News

Leading flow chemistry specialists Vapourtec (Cambridge, UK) have expanded their team with the appointment of Joseph Moore as Research & Development Chemist.

Joseph, who graduated from University of Warwick with a Chemistry degree in 2012, will work with the R & D team…

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Photochemical hydrogenation of a nitro compound

Date: 30 April 2015 | Category: News

This application note demonstrates a green photochemical route to the reduction of Nitro compounds. The powerful combination of Vapourtec’s V-3 pump and the UV-150 Photochemical reactor is utilized to deliver the photo catalyst as a slurry and provide precise control over the continuous flow photochemical reaction, even with the short reaction times of less than 1 minute. The TiO2 photo catalyst is safe, cheap and simply removed by filtration. There is also a fascinating comparison of the performance of three different 365 nm light sources; filtered mercury lamp, LED Gen-1 and LED Gen-2. The Gen-2 LED achieves comparable throughput of the mercury lamp while consuming <50% of the power.

high intensity UV light reactor

Generation and trapping of ketones in flow

Date: 19 March 2015 | Category: News

Researchers at the University of Southampton and GlaxoSmithKline have used Vapourtec’s R-Series flow chemistry system to synthesise Ketones in Flow by thermal sigmatropic rearrangement of alkoxyalkynes, and their trapping with amines or alcohols to provide amides and esters.

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Flow chem systems on show in Denver

Date: 17 March 2015 | Category: News

Vapourtec (Cambridge, UK) will be exhibiting their flow chemistry systems and latest reactor technologies at the forthcoming 249th ACS (American Chemical Society) National Meeting and Exposition, to be held in Denver (March 22-24) (booth 1307). Cited in over 150 peer-reviewed publications to date, Vapourtec will be showcasing their modular R-Series flow chemistry systems as well as the innovative UV-150 photochemical reactor to delegates attending the event.

Wundermaschine - Vapourtec

Vapourtec hails flow chemistry Europe a success

Date: 04 March 2015 | Category: News

Vapourtec (Cambridge, UK) has returned from the recent Flow Chemistry Europe event in Berlin encouraged by high levels of interest shown in its UV-150 photochemical reactor as well as the R-Series and E-Series flow chemistry systems. Vapourtec Sales Specialist Stacey Crane commented: “Our E-Series and R-Series systems were frequently cited in many of the presentations that showcased some of the latest methods and breakthroughs in flow chemistry research. This provided invaluable exposure for the potential of our systems.

Wundermaschine - Vapourtec

The miracle machine that makes drugs cheaper

Date: 03 March 2015 | Category: News

Vapourtec’s E-Series flow chemistry system has been described in the popular German newspaper Bild as a “Wundermaschine” that dramatically reduces the cost of manufacturing drugs. The article (dated 28 February) profiles the pioneering research work of Professor Peter Seeberger and his young team of scientists at the Max Planck Institute of Colloids and Interfaces in Dahlem, Germany.

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Vapourtec on show at Flowchem Europe

Date: 09 February 2015 | Category: News

Cambridge (UK) based Vapourtec will be showcasing the very latest continuous processing systems at the forthcoming Flow Chemistry Europe event in Berlin, Germany (17-18 February 2015). Their conference presence (stand 07) will feature the E-Series, a robust, easy to use and affordable flow chemistry system that has contributed towards the 12-year-old company being cited for research breakthroughs in over 150 peer review publications.

Vapourtec (Cambridge, UK) has hailed its presence at the recent Flow Chemistry India conference in Mumbai as a great success with significant interest shown in its array of flow chemistry and photochemistry technology

Flowchem India delivers for Vapourtec

Date: 09 February 2015 | Category: News

Vapourtec (Cambridge, UK) has hailed its presence at the recent Flow Chemistry India conference in Mumbai as a great success with significant interest shown in its array of flow chemistry and photochemistry technology. Vapourtec’s Sales and Application Specialist Andrew Mansfield reported a strong level of engagement by education, research and pharmaceutical clients from across India.

high intensity UV light reactor

Shedding LED light on photochemical research

Date: 04 February 2015 | Category: News

Suffolk (UK) based chemistry engineering specialists Vapourtec have launched a second generation LED light source (Gen-2) which increases the range of applications for its innovative, continuous flow UV-150 photochemical reactor. With flow chemistry processes increasingly replacing the more traditional batch approach within photochemistry, the rate of innovation and development for UV LEDs continues to grow with outputs doubling year on year.

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CRO recognises the benefits of continuous processing

Date: 15 January 2015 | Category: News

Regis Technologies, a contract research organisation (CRO) based near Chicago, has just taken delivery of a new R-Series continuous processing chemistry system designed and manufactured by UK-based Vapourtec Ltd. Chemists at Regis will use the flow system to accelerate process research and development and to perform unique chemical reactions most efficiently under continuous mode from lab scale up to a kilo scale.

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Continuous flow of breakthroughs for Vapourtec

Date: 11 December 2014 | Category: News

Flow chemistry systems designed and manufactured by Suffolk (UK) based Vapourtec have recently reached the impressive milestone of having been cited in 150 peer review publications. By way of a comparison Vapourtec’s two closest competitors in flow chemistry technology have been mentioned in 51 and 40 publications respectively.

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Chemical assembly systems: Layered control for divergent, continuous, multistep syntheses of active pharmaceutical ingredients

Date: 03 December 2014 | Category: News

Using the Vapourtec R-Series flow chemistry system researchers from the Max-Planck Institute of Chemistry and Biology have developed an approach to deliver a range of active pharmaceutical ingredients (API’s) in a continuous process. The concept uses a non-iterative chemical assembly system that uses a range of flow chemistry modules that can be linked and interchanged to gain access to an increased chemical space.

high intensity UV light reactor

Continuous flow magnetisation of functionalized heterocycles and acrylates with the Knochel-Hauser base (TMPMgCl·LiCl)

Date: 03 December 2014 | Category: News

Using the Vapourtec E-Series flow chemistry system researchers from the Ludwig-Maximilians-Universitat Munchen have shown a procedure for functionalizing a range of heterocycles and various sensitive acrylates using the strong, non-nucleotide Knochel-Hauser base TMPMgCl.LiCl and the subsequent quenching with various electrophiles. The ability of the advanced Vapourtec V-3 pump to continuously process reagents of this type allows for the multi-gram scale-up of these reactions previously limited to small scale.

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Reactor technology drives photochemistry

Date: 01 November 2014 | Category: News

This article will outline a few of the most common types of photochemical reaction and analyse the key features of a reactor, considering the light sources currently available. Finally, it will showcase just a few of the many real world applications for photochemistry.

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MOF research goes with the flow approach

Date: 14 October 2014 | Category: News

Recently published research into the production of Metal-Organic Frameworks (MOFs) utilising Vapourtec flow chemistry technology has revealed the substantial benefits of adopting a continuous flow process over the traditional batch approach. MOFs exhibit similar structures to naturally occurring Zeolites however their properties can be synthetically tuned providing a multitude of potential industrial applications including the storage, separation and triggered release of gases, drug molecules or toxins due to the porous nature of MOF compounds.

LED Lamp

Photochemistry potential revealed in application notes

Date: 07 October 2014 | Category: News

The incredibly powerful potential of photochemistry is revealed in four application notes recently posted by Suffolk-based flow chemistry engineering firm Vapourtec. The four application notes cover ‘Synthesis of Artemisinin using E-Series and UV-150 reactor’ (Application Note 39), ‘α-Photodecarboxylation of Phthaloyl Glycine’ (38), ‘Photochemical Transformation of Methyl Coumalate’ (37) and ‘[2+2] Photocycloaddtion of Maleimide and 1-Hexyne’ (36).

vapourtec photochemical reactor

Flow v batch photochemistry: A like for like comparison

Date: 24 September 2014 | Category: News

There are a number of key advantages of a continuous flow approach to photochemistry over a traditional batch method including consistent light penetration, controlled exposure times, precise temperature control and easy scalability as well as the removal of photochemical products from the irradiated area. Comparing the two methods when it comes to the Photochemical Transformation of Methyl Coumalate reveals the substantial efficiencies and economies that can be accrued from the flow chemistry route.

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Continuous synthesis of artemisinin-derived medicines

Date: 17 September 2014 | Category: News

Using the Vapourtec R-Series flow chemistry system researchers from the Max-Planck Institute of Colloids and Interfaces have developed an inexpensive, large scale synthesis of a range of anti-Malaria drugs under continuous flow conditions. The continuous, divergent synthesis system is coupled to continuous purification and is capable of producing four anti-malarial APIs.

R-Series flow chemistry system

Vapourtec sees flow chemistry growth in India

Date: 08 September 2014 | Category: News

UK chemistry engineering firm Vapourtec is establishing a burgeoning market for its flow chemistry systems across India with the continued development of a distribution partnership with Mumbai-based Pi-Process Intensification. Pi-Process Intensification have been acting as distributors for Vapourtec’s R-Series systems for the past three years and will now also be distributing their E-Series system.

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