News

Last month, Dr Manuel Nuño installed another Peptide-ExplorerLT for fast-flow solid phase peptide synthesis (FF-SPPS). For the next two-months the Bachem UK (St Helens) site will be equipped with Vapourtec’s unique Variable Bed Flow Reactor (VBFR) technology for FF-SPPS. Dr Ga...

Vapourtec’s eBPR is a self-contained, electronically adjustable back pressure regulator that does not require any external reference gas pressure. Back pressure regulators (BPRs) have, until now, been fixed and manually or electronically adjustable through the external contr...

Lucas Kambanis, Anthony Ayoub, Max J. Bedding, Peter H. G. Egelund, Joshua W. C. Maxwell, Charlotte Franck, Lucien Lambrechts, Paige M. E. Hawkins, Timothy S. Chisholm, Joel P. Mackay, Emma Sierecki, Yann Gambin, Sameer S. Kulkarni, and Richard J. Payne* The Payne group at the...

Vapourtec has developed an online UV detector designed specifically for peptide synthesis and flow chemistry applications. Rugged, reliable and compact, the Fmoc-UV has no moving parts and features a low-cost flow cell that can be easily replaced in the event of any blockages....

The Vapourtec team recently attended the ECOFR XV conference in Manchester. Like the Olympics, this event takes place every four years, bringing together researchers from around the world. This year's focus was on the applications of radical chemistry in organic synthesis, materi...

Vapourtec is investing in the future of flow chemistry through a partnership with the organic chemistry team at the University of Bristol’s EPSRC Centre for Doctoral Training (CDT), headed up by Professor Varinder K Aggarwal. Over the next five years, a minimum of 70 PhD can...

Continuous-Flow Solid-Phase Peptide Synthesis to Enable Rapid, Multigram Deliveries of Peptides Kyle E. Ruhl*, Michael J. Di Maso*, Harrison B. Rose, Danielle M. Schultz, François Lévesque, Shane T. Grosser, Steven M. Silverman, Shasha Li, Nunzio Sciammetta, and Umar Faruk Ma...

Multiphase photochemistry in flow mode via an integrated continuous stirred tank reactor (CSTR) approach Antonella Ilenia Alfano*, Megan Smyth, Scott Wharry, Thomas S. Moody, Manuel Nuño, Chris Butters, and Marcus Baumann* The Baumann group at University College Dublin have ...

Once again, ACHEMA didn’t disappoint. This year, 2,842 exhibitors from 56 countries presented their products and services to 106,001 participants from 141 countries and we were proud to be among them. ACHEMA continues to be one of the largest events in the industry – at a mas...

Two key publications released recently within the same week demonstrate the breadth and impact of recent innovative work within the field of flow chemistry. The two papers demonstrate improvements within photochemistry and peptide synthesis utilising Vapourtec’s recently unv...

The growing role and potential of machine learning in chemistry, and particularly within flow chemistry, is being shown by Vapourtec and Accelerated Materials at the upcoming ACHEMA process industry exhibition (Frankfurt, June 10-14).

Although the use of bioreactions within mainstream organic chemistry is established, translation into flow chemistry has been slower. However, in recent years there have been significant advances in the field of flow biocatalysis. In particular, enzyme immobilisation has allowed the development of column or ‘packed-bed’ reactors. Our mini-review highlights a range of recently published enzyme-mediated transformations, where using flow mode often achieves higher yields, faster reaction rates, and better selectivity, as well as increased retention of enzyme activity when compared to the batch process.

Our Distributor Manager Ali Deuchars had a worthwhile trip to Mumbai, India last week, attending ChemExpo India 2024 and visiting potential and existing customers in the area.

The Vapourtec R-Series system was used by researchers at Novartis to safely scale-up the preparation of a preclinical candidate to over 100 g in a telescoped process requiring diazotization, azide formation and cyclisation, all of which are known to be hazardous if performed on larger scale.

Vapourtec CSO Dr. Manuel Nuño recently met with Prof. Thomas Wirth and it was the perfect occasion to ask him some questions about a recent high-profile publication in Science Advances entitled “Electric field–assisted anion-π catalysis on carbon nanotubes in electrochemical microfluidic devices”.

We highly recommend a recent publication by the Baumann group and Ley group, reviewing the role flow chemistry can have in new reaction discovery compared to batch chemistry. This review focuses specifically on four types of chemical processes - photochemistry, electrochemistry, high temperature reactions, and reactive intermediate reactions - where continuous flow has led to the discovery of many new reactions and reactivity patterns.

Broadening flow chemistry horizons over the past decade, Vapourtec’s E-Series flow chemistry system has reached the notable landmark of 300 installations around the globe. Firmly established over the last ten years as the leading entry-level flow chemistry system, the E-Series has also been pivotal in many key research breakthroughs, appearing in over 250 peer-reviewed publications.

Last week Dr Manuel Nuño and Dr Keren Abecassis attended a mini-symposium organised by the British Peptide Society and the Protein & Peptide Science Group of the Royal Society of Chemistry. This peptide chemistry-focused event was a celebration of the work of Dr Eric Athe...

Vapourtec Director Duncan Guthrie and CSO Dr. Manuel Nuño attended Flow Chemistry Europe (FCE) 2024 in Málaga, Spain last week. The 12th iteration of this annual, must-attend, flow chemistry event was a huge success.