Peptide-Scaleup

Configuration Overview

The Peptide-Scaleup is designed for the peptide chemist aiming to scaleup their peptides where synthesis time is critical. The Peptide-Scaleup is an advanced alternative to traditional room temperature batch scaleup peptide synthesizers. Typically a 30-mer peptide can be synthesized at 4 mmol scale in just 16 hours.

• Synthesis scale 0.5 mmol to 5.0 mmol
• Highest quality crude peptides at large scale, minimises demands on purification
• Heated reactors (VBFR) ensures fast cycle times even at largest scale
• State of the art peptide synthesis software including sequence generator with automated addition of side chain(s)
• Uses Vapourtec’s patented reactor technology (VBFR) for continuous flow single pass SPPS
• Fmoc solid phase peptide chemistry with DIC and oxyma activation
• Minimises solvent and reagent usage compared with competing products
• Continuous in-line analytics including resin solvation data and UV absorption data
• A synthesis optimised on the Peptide-Explorer can be transferred to the Peptide-Pilot without further development