Glass chip microreactors and micromixers – Features

The chip reactor, mixer housing, and reactor range offer an effective solution for challenging reactions. Microscale channels provide rapid mixing, ideal for mixing-limited processes, while the high surface-area-to-volume ratio enables excellent heat transfer for fast and exothermic reactions. Temperature is precisely controlled using chilled gas for cooling and circulated hot air for heating, allowing rapid and accurate temperature changes. Small internal volumes reduce risk in hazardous chemistry and minimise reagent use.

Vapourtec Chip micro reactor

Application examples

  • Fast and exothermic reactions. High surface area to volume ratio
  • Mixing limited reactions. Microscale channels enable rapid mixing
  • Hazardous chemistry. Small internal volumes reduces risk
  • Screening and optimisation. Small reactor volume reduces reagent consumption
  • Amide formation and other reactions in mixed phases

Chip reactors and mixers features

  • Temperature range – 40 C to 150 °C
  • Reactor volumes 0.2 ml to 1.7 ml
  • Residence times 2 s to 30 minutes
  • Two chip reactors or mixers can be fitted in each housing
  • Pressure up to 20 bar at 150 °C
  • 7 standard designs, specials on request
  • Wetted materials – Borosilicate glass
  • Suitable for homogeneous reactions only

Key advantages

The microscale channels enable rapid mixing and efficient heat transfer, ideal for fast, exothermic, and mixing-limited reactions. Precise temperature control using chilled gas and heated air ensures quick response. Low internal volumes enhance safety, reduce reagent use, and support efficient screening, particularly for hazardous and mixed-phase reactions

Range of microreactors

Each microchip reactor comes in a default size of 115 x 60 x 6 mm. The structure of the channels varies depending on what conditions and mixing types required.


LTF-MS – 50-1273

Mixing volume 0.2 ml

Channel size: 1 mm

0.5 – 20 ml / min / channel

With two input channels, and a short duration, this reactor is not prone to blockage


LTF-MX – 50-1268

Mixing volume 0.2 ml

Channel size: 1 mm

0.1 – 10 ml / min / channel

Two input channels, short duration, for quick mixture-intensive substances


LTF-V – 50-1272

Mixing volume 1.7 ml

Channel size: 1 mm

Single channel, reduced turbulent flow, for increased exposure time


LTF-VS – 50-1269

Mixing volume 1.1 ml

Channel size: 1 mm

Single channel, for mixture-intensive substances and increased exposure time


Reactor 1 – 40-1773

Mixing volume 1.5 ml

Channel size: 1 mm

Two input channels, for mixture-intensive substances and long exposure time


Reactor 2 – 40-1774

Mixing volume 1.0 ml

Channel size: 1 mm

0.25 ml pre-conditioning volume for both input channels

Two input channels, allow both reagents to reach reaction conditions before mixing, for mixture-intensive substances and long exposure time


Reactor 3 – 40-1775

Mixing volume 0.6 ml

Secondary mixing volume 0.25 ml

Channel size: 1 mm

0.25 ml pre-conditioning volume for both input channels

Third channel with 0.25 ml pre-conditioning for quenching agent

Three input channels, allow all three reagents reach reaction conditions before mixing, the third channel mixes after an initial 0.6 ml, for mixture-intensive and delayed/quenching substances

 


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