Newsletters

    Here you can see previous issues of the Flow Synthesis Online newsletter.

    Static mixer reactor

    8 new publications & 4 application notes – Vapourtec Spring Newsletter 2016

    Date: May 2016

    Included in this newsletter:

    • 8 new publications utilising Vapourtec systems
    • 4 new application notes
    • New reactor with full length static mixer
    • New reactor for immobilised photo catalysts
    • Low pressure mercury lamps now available for UV-150
    • New set of long-pass filters for UV-150
    Download Newsletter as PDF

    LED Lamp

    New Publications & New Features – Vapourtec Spring Newsletter

    Date: April 2015

    Included in this newsletter:

    • 8 new publications utilising Vapourtec systems
    • New suspension/slurry pump module
    • Nanoparticle synthesis under flow conditions
    • LED continuous flow photochemical reactor
    • Further growth in flow chemistry
    • Continuous liquid-liquid extraction
    Download Newsletter as PDF

    Vapourtec-R2S-slurry-flow-chemistry-pump-module

    12 new publications – Vapourtec Winter 2014 newsletter

    Date: December 2014

    Included in this newsletter:

    • Introducing the R2-S new Suspension / light slurry pump module
    • Continuous flow of publications tops 150 for Vapourtec systems
    • Vapourtec sees growth in India
    • Flow v batch Photochemistry – a like-for-like comparison
    • Meetings, conferences or exhibitions where you can see Vapourtec products and talk to Vapourtec staff
    • Synthesis of Artemisinin via the Photooxidation of Dihydroartemisinic Acid
    • Preparation of Silver Nanoparticles under Continuous Flow Conditions
    • 12 new publications in this issue
    Download Newsletter as PDF

    Vapourtec-R-Series-fraction-collection

    15 new flow chemistry publications – Vapourtec spring newsletter

    Date: March 2014

    Welcome to our March e-newsletter! We’re excited to announce that Vapourtec just installed its 200th R-Series system. We’d like to say a big thank you to all our customers, who have moved chemistry forward enormously and helped Vapourtec reach this significant milestone.

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    E-Series-wizard-reactor-choice

    New Tools for Easier Flow Chemistry

    Date: August 2013

    Included in this newsletter:

    • E-Series tools. We take a look at the simple but powerful tools built into every E-Series flow chemistry system, including the ability to run an automated flow experiment with no manual intervention
    • Meetings, conferences or exhibitions where you can see Vapourtec products and talk to Vapourtec staff
    • A New Publication Showing the Use of the E-Series System for Organometallic Chemistry
    • Alkyl-Aryl Negishi Cross-Coupling in Flow
    • Palladium-Catalyzed Decarboxylative Couplings using Oxygen as the Oxidant
    • Integrated Synthesis and Testing of Substituted Xanthine Based DPP4 Inhibitors
    • Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis
    • Rapid Generation of Isothiocyanates in Flo
    Download Newsletter as PDF

    Inert gas blanketing-2

    Organometallics and Flow Chemistry teaching

    Date: February 2013

    Included in this newsletter:

    • The Vapourtec E-Series shows what it can do with organometallic reagents
    • E-Series teaching materials – ready made undergraduate lab course, free with each instrument
    • Chromium Arene Synthesis
    • Butyl Lithium reactions with the new E-Series
    • Grignard Reactions with the new E-Series
    • University of Montreal makes big flow chemistry investment
    • Two very informative webinars you might want to check out
    • See what’s coming up this year on the flow chemistry event calendar
    • Continuous Synthesis and Use of N-Heterocyclic Carbene Copper(I) Complexes from Insoluble Cu2O
    • Continuous-flow generation of diazoesters and their direct use in S-H and P-H insertion reactions
    • Synthesis of RAFT Block Copolymers in multi-stage flow
    • Synthesis of Carbohydrate-Functionalised Sequence-Defined Oligo(amidoamine)s by Photochemical ThiolEne Coupling
    • Ozonolysis of Some Complex Organic Substrates in Flow
    • Synthesis of Imatinib and analogues utilising flow
    Download Newsletter as PDF

    ht_tube_reactor

    Neat Synthesis: Faster, greener and cheaper

    Date: November 2012

    Included in this newsletter:

    • More solvent free chemistry, offering both higher throughput and a much greener approach
    • Some high pressure flow chemistry, using liquefied gaseous reagents at elevated temperatures
    • A new application showcasing the Vapourtec acid resistant gas/liquid membrane reactor
    • Flow synthesis of organic electronic materials
    • Preparation of arene chromium tricarbonyl complexes in flow
    • Light-Initiated preparation of functionalized polystyrene monoliths
    Download Newsletter as PDF

    Vapourtec logo

    A breakthrough in flow chemistry …

    Date: August 2012

    Included in this newsletter:

    • Nitro reduction with iron granules
    • Amidocarbonylation with CO using a gas/liquid reactor
    • Continuous pumped fluorination with DAST
    • Continuous flow synthesis and inline purification using simulated moving bed (SMB)
    • Continuous end group removal of polymers using a RAFT process
    • A “Catch-React-Release” Method for the Flow Synthesis of 2-Aminopyrimidines
    • Asymmetric Homogeneous Hydrogenation in Flow using a Tube-in-Tube Reactor and more
    Download Newsletter as PDF

    V3 pump line diagram

    Solvent Free Reactions : Very high throughput

    Date: September 2012

    Included in this newsletter:

    • We look “under the hood” of the Vapourtec V-3 pump, (Above) which is at the heart of the new E-Series flow chemistry system. Several of you have asked about the technology behind it, and here we describe how it works, and what it makes possible.
    • An example of solvent free (ie neat) synthesis, with throughput in excess of 400g/hr
    • O-Methylation of a carboxylic acid with TMS diazomethane
    Download Newsletter as PDF

    CycloFluidocLogo

    Automated medchem and flow hydrogenation

    Date: May 2012

    Included in this newsletter:

    • An exciting new Vapourtec collaboration in India
    • A case study of a fully automated discovery platform for hit to lead optimisation
    • New publications
    • Vapourtec and Pi-Process Intensification Experts LLP
    • Max Planck lnstitute ramps up their flow chemistry work
    • Continuous Flow Hydrogenation with the Vapourtec gas/liquid reactor
    • Case Study – Cyclofluidic Ltd
    • Events diary
    • Publications
    Download Newsletter as PDF

    rseries04

    Mixing & dispersion, ionic liquids, and high pressures

    Date: March 2012

    Included in this newsletter:

    • A must-read publication from MIT examining in depth the issues of mixing, dispersion and scaleup in continuous flow reactors
    • A new Vapourtec/METTLER TOLEDO joint white paper showing the use of the FlowIRTM system in conjunction with the Vapourtec R SeriesTM System for real time monitoring of reaction output
    • The unveiling of the new Vapourtec High Pressure flow system
    • METTLER TOLEDO FlowIR™ / Vapourtec white paper
    • The new Vapourtec High Pressure Pump Module
    • Synthesizing ionic liquids using the Vapourtec R SeriesTM
    • Discount registration for the Flow Chemistry Congress meeting in Boston
    • Mixing, dispersion and scaleup in continuous flow reactors
    • Example of scale up to > 2kg
    • Phase Transfer Catalysis in flow
    • Two reviews looking at the flow chemistry world from different perspectives
    Download Newsletter as PDF

    Column-cooled-vaportec_edit0013

    New Application Notes and Tropical Diseases

    Date: January 2012

    Included in this newsletter:

    • New low cost flow route for synthesis of key anti malarial drug announced
    • Revisiting the cooled column
    • Vapourtec Flow Workshop
    • 3 new application notes now available
    • Where you can meet Vapourtec in 2012 (updated)
    • Flow synthesis of the anti malarial drug Artemisinin
    • Homogeneous catalyst produced on demand from a solid packed bed
    • Plus three more interesting new papers
    • Plus a new review of flow technology
    Download Newsletter as PDF

    flowIR

    FTIR integration, dual reactors and exotherms

    Date: November 2011

    Included in this newsletter:

    • Integration of METTLER TOLEDO FlowIR(TM) with Vapourtec system
    • New “Dual Core” coil reactors – two reactors in one
    • New application notes available, showing how to use the gas/liquid reactor
    • How to safely investigate and actually quantify exotherms with the R Series
    • Where you can see Vapourtec in 2012 (and some events in 2011 too)
    • Vapourtec users reach 50 publications (plus 5 more in this issue !)
    • Flow Chemistry on TV !
    • Plus a good collection of new publications
    • Two comprehensive review articles give a great “state of play” of the continuous flow field
    Download Newsletter as PDF

    Vapourtec-wireless-flow-chemistry

    Automation, integration and remote access

    Date: September 2011

    Included in this newsletter:

    • A new Vapourtec remote control and automation facility
    • More gas/liquid chemistry
    • The new Journal of Flow Chemistry is now launched
    • Plus photolysis, polymerisation and lots more
    Download Newsletter as PDF

    VTec_Thurs_030714_LowRes_013

    Inert gas & Inert reactors

    Date: July 2011

    Included in this newsletter:

    • Convenient inert gas blanketing of reagents
    • New polymer coated stainless steel tube reactors
    • A selection of interesting publications
    Download Newsletter as PDF

    cisro logo

    NEW gas reactor enables hydrogenation, carbonylation in flow

    Date: May 2011

    Included in this newsletter:

    • The new Vapourtec Gas/Liquid Reactor is unveiled
    • CSIRO in Australia
    • Nitration with fuming nitric acid at 97g/hr
    • Total synthesis of Fluoxetine in flow
    • Library synthesis of Trisubstituted Pyrrolidines
    Download Newsletter as PDF

    UV detector

    UV-triggered product collection

    Date: March 2011

    Included in this newsletter:

    • 3 new product announcements including UV Triggered Collection of Product peaks
    • A new “Case Study” feature
    • A chance to get half price registration for the Flow Chemistry Congress in Boston
    • Lots of new flow publications ranging from azide chemistry through magnetic mixing to RAFT polymerizatio
    Download Newsletter as PDF

    staff_1

    Inline sensing, collaboration and a telegram from the Queen

    Date: January 2011

    Included in this newsletter:

    • A special day for Vapourtec
    • New academic collaborations announced
    • New office to open in Malaysia
    • New manifold for inline sensor temperature control
    • New tube reactor with heated mixing
    • 7 new papers
    Download Newsletter as PDF

    Vapourtec-flow-wizard

    Open Access flow chemistry

    Date: November 2010

    Included in this newsletter:

    • Flow Ozonolysis
    • The NEW Open Access Vapourtec System
    • Flow chemistry publications from the last few weeks
    Download Newsletter as PDF

    Column-cooled-vaportec_edit0013

    Cooled columns and Ultrasound

    Date: September 2010

    Included in this newsletter:

    • Dealing with organometallic reagents
    • New Cooled column reactor
    • Where and when to see Vapourtec systems in action
    • New flow chemistry publications from the last few weeks
    Download Newsletter as PDF

    vaportec_edit0012

    Ozonolysis with the Vapourtec Flow Chemistry System

    Date: May 2010

    Included in this newsletter:

    • Ozonolysis in the Vapourtec R series, Vapour Pressure of Solvents at High Temps
    • Pumping of BuLi now possible
    • Where and when to see Vapourtec systems in action
    • 5 new flow chemistry publications from the last few weeks
    Download Newsletter as PDF

    march10

    There will be growth in the spring…

    Date: March 2010

    This issue’s theme is growth. We have product announcements about being able to more, details of a new annual Flow Chemistry event, plus more interesting new publications than ever. And some Vapourtec news too.

    Download Newsletter as PDF

    cooeld reactor vapourtec

    Flow reactions cooled to -70C !

    Date: January 2010

    This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

    Download Newsletter as PDF

    R-series inert gas balnketing

    50g/hr nitration with fuming nitric acid in flow !

    Date: November 2009

    There’s clearly a lot of technology development going on in flow ! Below you can see Vapourtec’s announcement of the first true nitration capable flow chemistry system. There are also links to a free webinar demonstrating Mettler Toledo’s ReactIR™ flow cell and publications involving online HPLC (Merck) , and online phase separation (University of Cardiff).

    Download Newsletter as PDF

    sept09

    When is a tube not a tube ?

    Date: September 2009

    This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

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    july09

    It’s just a phase…

    Date: July 2009

    In this issue we take a look at liquid/liquid biphasic reactions in flow.

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    may09

    Flow chemistry with a Click

    Date: May 2009

    This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

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    march09

    More flexibility than ever

    Date: March 2009

    This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

    Download Newsletter as PDF

    jan09

    Get more reactions done in less time.

    Date: January 2009

    The theme for this issue is reaction optimisation. If you have an interest in rapid reaction setup, optimisation and scaleup, and you would like to produce more in less time, read on.

    Download Newsletter as PDF

    nov08

    Flow Synthesis Online

    Date: November 2008

    This publication is released bi-monthly and will showcase new applications, events, and equipment in the Flow Synthesis world.

    Download Newsletter as PDF

    Get in touch

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    Call us on +44 (0)1284 728659 or Email us