RS-300 – Multiple reactions fully automated

R-series flow chemistry system RS-300

Configuration Overview

The RS-300 is a more complex system, with some room for expansion or customisation. It is still completely modular, compatible with simpler and older systems. It includes automated control, a product collector, 4 pumps and a number of reactors. It is ideal for medical chemistry and process research groups.

The RS-300 package contains:

  • 2x R-series pump modules for maximum reagent delivery flexibility
  • A fraction collector for automated collection
  • Flow commander professional control software for automation of multiple pumps
  • A range of reactors offering diverse conditions
  • An equipment frame and drip trays

R4 flow reactor heater


The RS-300 comes with a standard heated, cooled and high temperature tube reactors and the standard heated column reactor. As with all R-Series, the system is completely modular and can support the whole range of reactor types, all interchangeable in seconds. Other reactors can be found on the reactors page and include:

  • Heated or cooled
  • Tube or column
  • Regular or pre-mixing
  • Polymer, stainless steel or Cu / Ag / Zn tube reactors for catalysed reactions.
  • Gas / liquid reactor
  • UV-150 Photochemical reactor
  • Glass microchip reactors
  • Up to 4 reaction steps as standard

R2S single flow chemistry pump module

Pump Modules

The RS-300 comes with two R2-C+ pump modules as standard. There are a number of R-Series pumps displayed on the pumping modules page, each with its own advantage and capability for reactions and reagents. The RS-300 already uses 4 pumps, however the pump can still be  interchanged.

All pumps are simple, accurate and reliable, and with the correct pump, can carry out reactions using:

  • Large range of solvents
  • Volatile solvents
  • Highly reactive reagents (e.g. BuLi, DIBAL)
  • Strong acids
  • High pressure
  • Sample injection loops

All pump modules come with Vapourtec’s continuous monitoring system to ensure displayed flow rate is always accurate.



The RS-300 includes the “FlowCommander” software. Choose from simple push button front panel or easy to use touchscreen.

Flow Commander will:

  • Automate the mundane
  • Run a list of reactions unattended
  • Log, save and chart data
  • Predict dispersion
  • Save reaction setup for later re-use or sharing
  • Export system diagrams for reports and publications
  • It also comes with the alternative “Flow Wizard” interface which is optimised for occasional manual use


Expansion and customisation

The RS-300 is a relatively complex configuration, however it is still customisable. The R-Series can grow to suit your needs. Including the previous sections, the RS-300 can be expanded to include:

  • More reactors
  • Autosampler which can inject different reagents into each one of a list of automated unattended reactions
  • UV sensor (which can be used to trigger collection of product peaks)
  • Integration with METTLER TOLEDO FlowIR system (which can be used to trigger collection of product peaks)

All new developments are backwardly compatible, so even the oldest systems can accept all the latest capabilities and vise versa.

Need more help with the R-Series?

Please use the contact methods below to talk to us about our R-Series products and services. We aim to respond to your enquiry within 24 hours.

Call us on +44 (0)1284 728659 or Email us

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