Publications

Peer reviewed publications citing Vapourtec

The following (non-exhaustive) list of papers shows peer-reviewed work that has been published using the Vapourtec R-Series and E-Series flow chemistry systems.  As new work is continually published, please check here for updates.

Use the filter tools to see the chemical applications that are possible, but note that most published papers will require a journal subscription.

Download a list of all publications citing Vapourtec

Optimizing Continuous‐Flow Biocatalysis with 3D‐Printing and Inline IR Monitoring

Enzymatic biocatalysis typically generates less waste, uses less water, and minimizes energy consumption compared to traditional chemical methods. Efficient, cell‐free biosynthesis relies on the reuse of its valuable biocatalysts. Immobilization of enzymes on solid supports, su...

Optimizing Continuous‐Flow Biocatalysis with 3D‐Printing and Inline IR Monitoring
  • Spano, M
  • Pamidi, A
  • Liu, M
  • Evans, A
  • Weiss, G
  • University of California Irvine University of California Department of Chemistry Irvine CA 92697-2025 United States
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Automated One-pot Library Synthesis with Aldehydes as Radical Precursors

The increased demand for the synthesis of enriched hybridized Csp3 motifs and the urgency of discovering new drug molecules require the development of more efficient technologies and synthetic tools to accelerate drug discovery processes. Herein, we report a fully automated strat...

  • Luguera Ruiz, A
  • Pijper, B
  • Linares, M
  • Cañellas, S
  • Protti, S
  • Fagnoni, M
  • Alcazar, J
  • University of Pavia
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Continuous Enantioselective α-Alkylation of Ketones via Direct Photoexcitation

Motivated by the scarcity of enantioselective direct intermolecular α-alkylation reactions of ketones with simple alkyl halides, we report a photo-organocatalytic process to access diethyl 2-(2-oxocyclohexyl)malonate and derivatives in good yield and enantioselectivity. The reac...

Continuous Enantioselective α-Alkylation of Ketones via Direct Photoexcitation
  • Weiser, M
  • Pálvölgyi, ÁM
  • Weil, M
  • Bica-Schröder, K
  • Institute of Applied Synthetic Chemistry, TU Wien, 1060 Vienna, Austria
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Multiphase photochemistry in flow mode via an integrated continuous stirred tank reactor (CSTR) approach

A new photochemical CSTR system capable of handling solids in scaled continuous processes is presented. High-power UV-LEDs are integrated in these CSTRs containing an insoluble base that aids in generating pyrazolines via cycloaddition between alkenes and in situ generated diazo ...

Multiphase photochemistry in flow mode via an integrated continuous stirred tank reactor (CSTR) approach
  • Heterogeneous catalysis
  • Photocatalysis
  • Alfano, AI
  • Smyth, M
  • Wharry, S
  • Moody, TS
  • Nuño, M
  • Butters, C
  • Baumann, M
  • School of Chemistry, University College Dublin, Science Centre South, Dublin 4, Ireland
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Enabling Electrochemical C-O and C-N Arylation Libraries using Alternating Polarity in Flow

Etherification and amination of aryl halide scaffolds are commonly used reactions in parallel medicinal chemistry to rapidly scan structure-activity relationships with abundant building blocks. Electrochemical methods for aryl etherification and amination demonstrate broad functi...

  • Morvan, J
  • Kuijpers, K
  • Fanfair, D
  • Tang, B
  • Bartkowiak, K
  • Van eynde, L
  • Renders, E
  • Wolkenberg, S
  • Alcazar, J
  • Buijnsters, P
  • Carvalho, M
  • Jones, A
  • Janssen Research & Development
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