News

Carbon monoxide generation in flow

Ley Group control carbon monoxide generation in flow

A recent, published research breakthrough by the group of Steven Ley at the University of Cambridge has led to the ‘Controlled generation and use of CO in flow’. The paper describes the use of a tube-in-tube reactor for the safe hydrolysis of Ozalyl Chloride using a NaOH solution. This produces Carbon Monoxide in the outer stream which then passes through AF-2400 semi-permeable inner tubing to enrich reaction streams. By using this approach, carbonylations can be successfully performed in flow without the use of pressurized gas cylinders.

Date: April 14, 2016 | Category: News
Vapourtec-R2S-slurry-flow-chemistry-pump-module

Vapourtec shows flow chemistry potential

Vapourtec shows flow chemistry potential with R2S and UV-150 at Continuous Flow Technology conference Flow chemistry engineering specialists Vapourtec will be showing their modular R-Series flow chemistry system along with the UV-150 Photochemical Reactor at the Continuous Flow Technology conference (Cambridge, March 14-16).

Date: March 11, 2016 | Category: News
Steve_Ley_group_vapourtec

Opening up novel, forbidden chemical space

Vapourtec’s continuous flow technology has played a key role in a recent breakthrough announced in Chemistry World by Steven Ley’s University of Cambridge team. Professor Ley’s team has managed to harness an explosive chemical class to create organic molecules and form novel bonds between carbon atoms. The process involves continuously diluted, small volume flows of highly reactive diazo reagents to form up to four carbon-carbon bonds without any isolation of intermediate molecules.

Date: February 11, 2016 | Category: News
R_Series_UV-150_flow-chemistry-systems

Flow chemistry Europe 2016 showcases R-series with UV-150

Vapourtec (Cambridge, UK) will be showcasing the R-Series flow chemistry system together with the innovative UV-150 Photochemical Reactor at the forthcoming 6th international conference of the Flow Chemistry Society (Cripps Court, Magdalene College, Cambridge, February 16-18) at booth 16.

Date: February 10, 2016 | Category: News
M_Oelgemoller photochemistry

Vapourtec launches reactor collaboration

Flow chemistry engineering firm Vapourtec has linked up with Associate Professor Michael Oelgemöller, one of the leading experts in green photochemistry and microflow photochemistry, for their latest photochemical reactor project. Currently Associate Dean of Research at James Cook University’s College of Science, Technology and Engineering in Australia, Michael’s research activities include synthetic organic photochemistry, solar photochemistry, the development of new photochemical synthesis tools and photochemical water treatment.

Date: January 28, 2016 | Category: News
Vapourtec_E-series-medchem-flow-chemistry-system

Vapourtec easy-Medchem system “live-demonstrations” on show in Mumbai

The forthcoming Flow Chemistry India conference (Mumbai, January 21-22) will see Vapourtec represented by our Indian distribution partners Pi-Process Intensification. Vapourtec’s easy-MedChem will be showcased in Mumbai. The easy-MedChem is a system aimed at chemists looking to do initial optimisation, followed by scale up optimisation. The system includes a tube reactor and column reactor for solid supported catalysts or reagents.

Date: January 15, 2016 | Category: News
Vapourtec Ltd team at premises near Cambridge UK

Rapid growth in flow chemistry

Interest in flow chemistry systems has doubled since 2010 according to UK-based flow chemistry engineering specialists Vapourtec who experienced a further 15% increase in turnover in 2015.

Date: January 13, 2016 | Category: News
High temperature tube reactor

High temperature uncatalysed esterification

Researchers at the University of Connecticut have utilised Vapourtec’s R-Series system to develop a catalyst free esterification of levulinic acid to ethyl levulinate, demonstrating a greener way to produce a compound heavily used in the flavour and fragrance industry. The r...

Date: September 17, 2015 | Category: News
E-Series-flow -chemistry-reactor

Focus on medicinal chemistry at ACS Boston

Specialist flow chemistry firm Vapourtec (Cambridge, UK) will be showcasing their easy-Medchem E-Series system at the forthcoming ACS (American Chemical Society) National Meeting & Exposition in Boston (August 16-18) Designed for medicinal chemistry labs, the easy-Medchem together with the pioneering UV-150 photochemical reactor, opens up novel chemical space for chemists.

Date: July 28, 2015 | Category: News

Further photochemical hydrogenation of nitro compounds

In our previous application note (No. 41) we reported on a green and efficient photochemical route to the reduction of 3-nitro-acetophenone to 3-amino-acetophenone. Challenged to show the broad applicability of the photochemical reduction using the low cost and green TiO2 photo catalyst we set out to extend this work to optimize the reduction of 3 further Nitro compounds. The compounds chosen exhibit a range of different reactivity, one compound was further chosen as a ‘real-world’ example, 4-(2-fluoro-4-nitrophenyl) morpholine being a key intermediate used in the synthesis of the oxazolidinone antibiotic Linezolid (Pfizer brand name ZYVOX®)

Date: July 7, 2015 | Category: News

Vapourtec ties in with Singapore distributor

Flow chemistry engineering firm Vapourtec (Cambridge, UK) has reinforced its presence in Asia by signing a distribution agreement with Singapore-based Polaris Science. Polaris Science supplies state-of-the-art laboratory equipment to the pharma industry and education sector in Singapore.

Date: July 7, 2015 | Category: News
Shanghai seminar Dr John Murray Vapourtec

Shanghai seminar reinforces China links

Flow chemistry technology firm Vapourtec has strengthened its links with China by organising a successful seminar that introduced the advantages of continuous chemical processing and showcased the latest technologies. Hosted by the Shanghai Research Institute of Chemistry Industry (SRICI) and organised by Vapourtec's Chinese distributor Tegent, the seminar attracted a large number of pharma and polymer industry specialists as well as academics from universities and institutes across China.

Date: July 6, 2015 | Category: News

Making a stand in Shanghai

Vapourtec’s new look booth at the CPhI China (Hall N1, booth N1D18) event in Shanghai is proving to be a big draw for visitors to the exposition with Stacey Crane and John Murray advising many interested attendees about the E-Series Medchem, easy-Photochem and R-Series flow chemistry systems. For more information visit

Date: June 25, 2015 | Category: News
high intensity UV light reactor

Flow chemistry potential revealed at Chemspec Europe

Vapourtec (Cambridge, UK), one of the leading global innovators in continuous chemical processing, will be displaying their latest flow chemistry technology at Chemspec Europe (Cologne, Germany June 24-25). Vapourtec will be exhibiting (booth G55A) the easy-Photochem system, which features the pioneering UV-150 photochemical reactor, in Cologne along with the R-Series, a modular flow chemistry system utilised by chemists around the world.

Date: June 3, 2015 | Category: News
E-Series-flow-photocemistry-reactor

Shanghai showcase for Vapourtec innovation

Vapourtec (Cambridge, UK), one of the world's leading innovators in flow chemistry systems, will be showcasing their latest technologies, in conjunction with Chinese distributors Tegent Scientific, at the CPhI China event (Shanghai, June 24-26). Visitors to the Vapourtec stand (Hall N1, booth N1D18) will be able to view the easy-Photochem flow chemistry system which features the pioneering UV-150 photochemical reactor.

Date: June 3, 2015 | Category: News

Vapourtec appoints experienced sales specialist

Vapourtec (Cambridge, UK), a leading global innovator in flow chemistry technology, has recently appointed experienced scientist John Murray to the position of Sales & Applications Specialist. John, a PhD qualified scientist, has 16 years of experience within the pharmaceutical industry, a key target market for Vapourtec’s range of continuous chemical process systems.

Date: May 27, 2015 | Category: News

Vapourtec teams up with Chemisky for distribution in Korea

Flow chemistry specialist Vapourtec has recently signed an exclusive distribution agreement with South Korean firm Chemisky, based in Seoul. The link followed a successful installation of Vapourtec's R-Series continuous process chemistry system at the Green Material & Process R&D Group at the Korean Institute of Technology (KITECH).

Date: May 21, 2015 | Category: News

New frontiers for Vapourtec with chinese collaboration

Vapourtec (Cambridge, UK) have announced a research collaboration with Professor Pengfei Li of the Frontier Institute of Science and Technology (FIST) at Xi'an Jiaotong University in China to develop novel, continuous flow, photochemical reactions using Vapourtec's easy-Photochem...

Date: May 14, 2015 | Category: News

Vapourtec expands research & development team

Leading flow chemistry specialists Vapourtec (Cambridge, UK) have expanded their team with the appointment of Joseph Moore as Research & Development Chemist. Joseph, who graduated from University of Warwick with a Chemistry degree in 2012, will work with the R & D team...

Date: May 6, 2015 | Category: News

Photochemical hydrogenation of a nitro compound

This application note demonstrates a green photochemical route to the reduction of Nitro compounds. The powerful combination of Vapourtec’s V-3 pump and the UV-150 Photochemical reactor is utilized to deliver the photo catalyst as a slurry and provide precise control over the continuous flow photochemical reaction, even with the short reaction times of less than 1 minute. The TiO2 photo catalyst is safe, cheap and simply removed by filtration. There is also a fascinating comparison of the performance of three different 365 nm light sources; filtered mercury lamp, LED Gen-1 and LED Gen-2. The Gen-2 LED achieves comparable throughput of the mercury lamp while consuming <50% of the power.

Date: April 30, 2015 | Category: News

Generation and trapping of ketones in flow

Researchers at the University of Southampton and GlaxoSmithKline have used Vapourtec’s R-Series flow chemistry system to synthesise Ketones in Flow by thermal sigmatropic rearrangement of alkoxyalkynes, and their trapping with amines or alcohols to provide amides and esters.

Date: March 19, 2015 | Category: News

Flow chem systems on show in Denver

Vapourtec (Cambridge, UK) will be exhibiting their flow chemistry systems and latest reactor technologies at the forthcoming 249th ACS (American Chemical Society) National Meeting and Exposition, to be held in Denver (March 22-24) (booth 1307). Cited in over 150 peer-reviewed publications to date, Vapourtec will be showcasing their modular R-Series flow chemistry systems as well as the innovative UV-150 photochemical reactor to delegates attending the event.

Date: March 17, 2015 | Category: News
Wundermaschine - Vapourtec

Vapourtec hails flow chemistry Europe a success

Vapourtec (Cambridge, UK) has returned from the recent Flow Chemistry Europe event in Berlin encouraged by high levels of interest shown in its UV-150 photochemical reactor as well as the R-Series and E-Series flow chemistry systems. Vapourtec Sales Specialist Stacey Crane commented: "Our E-Series and R-Series systems were frequently cited in many of the presentations that showcased some of the latest methods and breakthroughs in flow chemistry research. This provided invaluable exposure for the potential of our systems.

Date: March 4, 2015 | Category: News