News

Metal-free photocycloaddition of unactivated alkenes

Metal-free photocycloaddition of unactivated alkenes

Authors: Diarmuid O’Hanlon, Sharon Davin, Brian Glennon and Marcus Baumann*  The Baumann group at University College Dublin have reported the use of the Vapourtec E-Series flow chemistry system equipped with a medium-pressure Hg-lamp and a low-pass filter to undertake metal...

Date: 25 April 2025 | Category: News
peristaltic pump tube chemical compatibility

Peristaltic pump tube chemical compatibility

Vapourtec is excited to announce the release of a new peristaltic pump tube, identified as the “BLACK” tube. The BLACK tube has excellent chemical compatibility across the range of solvents and reagents currently supported by three different tube materials. Over the last 1...

Date: 15 April 2025 | Category: News
Vapourtec takes a stand with Bury Town FC

Vapourtec takes a stand with Bury Town FC

Specialist flow chemistry firm Vapourtec, based in Bury St Edmunds, is taking a stand with a ground advertising package at Bury Town FC. One of the club’s covered terraces will now be called the ‘The Vapourtec Stand’ and features the firm’s distinctive orange and purpl...

Date: 10 April 2025 | Category: News
R-Series installation at ANSTO to enhance deuterated molecules

R-Series installation at ANSTO to enhance deuterated molecules

The National Deuteration Facility (NDF) at the Australian Nuclear Science and Technology Organisation (ANSTO) has recently enhanced its research capabilities with the installation of a Vapourtec R-Series flow chemistry system. This addition marks a significant step forward in the...

Date: 27 March 2025 | Category: News
Headline News
cleaving oligonucleotides flow schematic

Enhancing the cleavage of Oligonucleotides

We are excited to be able to share the work of Scientists at Novo Nordisk who have applied flow chemistry to enhance the cleavage of oligonucleotides. The improvements reported are: Reducing the time for cleavage and complete deprotection to less than 3 minutes. Eliminati...

Date: 27 February 2025 | Category: Headline News, News
fixed bed reactor

Immobilised biocatalyst facilitates flow route to Danshensu

Authors: Valentina Marchini, Francesca Paradisi Valentina Marchini and Francesca Paradisi from The University of Bern have used a packed-bed reactor mounted within the Vapourtec R-Series modular flow chemistry system to synthesise danshensu [1], a pharmacological agent with s...

Date: 20 February 2025 | Category: News
Headline News
John Trant and Vapourtec case study

Case study: Trant Team University of Windsor, Canada

We report on an exciting collaboration, Vapourtec and the Trant Team from the University of Windsor are working together towards improving the efficiency of solid-phase peptide synthesis (SPPS) by using Fast Flow SPPS. Led by Professor John Trant, the Trant Team is the largest...

Date: 05 February 2025 | Category: Headline News, News
Headline News
Photochemically-enabled, post-translational production of C-terminal amides

Photochemical functionalisation of peptides and proteins

Authors: David Hymel, Felix Wojcik, Kim S. Halskov, Wouter F. J. Hogendorf, Sydnee C. Wong, Ben M. Williams, Asmus R. Mortensen, Nick Cox, Ayesha Misquith, Nanna B. Holländer, Finn Matthiesen, Suneet Mehrotra and Michael R. Harris  Scientists at Novo Nordisk have successfull...

Date: 16 January 2025 | Category: Headline News, News
Headline News
Seasons greetings from Vapourtec

Seasons Greetings from all the team at Vapourtec

Dear all, As 2024 comes to a close, we are keen to say a big thank you to our customers for their continued trust and support. This year saw the launch of the eBPR, an electronically adjustable back pressure regulator designed for precision and versatility, the photochemical v...

Date: 19 December 2024 | Category: Headline News, News
Metallaphotoredox decarboxylative arylation

Metallaphotoredox decarboxylative arylation

Flow chemistry facilitates scale-up to 200 mmol, maintaining excellent stereoselectivity and yields Martins Oderinde, Rajender Nallagonda and co-workers from the Bristol Myers Squibb Small Molecule Discovery Chemistry group have successfully used the Vapourtec UV-150 photochemic...

Date: 28 November 2024 | Category: News
Microscale High-Throughput Synthesis in Continuous Flow

Microscale High-Throughput Synthesis in Continuous Flow

Flow chemistry is a well-established method in research and development labs across industry and academia for screening of reagents, optimization of processes and generation of libraries of compounds. Flow chemistry allows safer and faster reactions, but also better control over ...

Date: 22 November 2024 | Category: News
Peptide-Builder high throughput automated peptide synthesizer

Accelerating Peptide Discovery with the Peptide-Builder

High-throughput experimentation (HTE) is a widely utilised technique in medicinal chemistry that enables the automated synthesis of extensive compound libraries. These compounds can then be tested against therapeutic targets, significantly accelerating the drug discovery process....

Date: 24 October 2024 | Category: News
Vapourtec install at Bachem.

Vapourtec’s Peptide-ExplorerLT installed at Bachem

Last month, Dr Manuel Nuño installed another Peptide-ExplorerLT for fast-flow solid phase peptide synthesis (FF-SPPS). For the next two-months the Bachem UK (St Helens) site will be equipped with Vapourtec’s unique Variable Bed Flow Reactor (VBFR) technology for FF-SPPS. Dr Ga...

Date: 03 October 2024 | Category: News
Vapourtec Meet the team: Harold Rupapa Chemistry Sales Specialist

Meet the team: Harold Rupapa

In the latest installment of our Meet the Team series, we’re introducing our Chemistry Sales Specialist; Harold Rupapa. Since joining in May Harold has focused on attending customer meetings, responding to enquiries, preparing quotes, and working with clients to configure syst...

Date: 18 September 2024 | Category: Meet The Team, News
Fmoc-UV detector

Compact UV detector for flow peptide synthesis

Vapourtec has developed an online UV detector designed specifically for peptide synthesis and flow chemistry applications. Rugged, reliable and compact, the Fmoc-UV has no moving parts and features a low-cost flow cell that can be easily replaced in the event of any blockages....

Date: 09 September 2024 | Category: News