Peptide chemistry

    Peptide synthesis chemistry

    Peptides chemistry is accomplished by coupling the carboxyl group of an amino acid to the amino group of a second amino acid molecule. Protecting groups are usually necessary because of the possibility of unintended reactions. In protein biosynthesis the peptide synthesis starts at the amino end. By contrast, in chemical peptide formation synthesis usually starts at the carboxyl end of the peptide, and proceeds toward the amino-terminus.

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    Examples of published literature for Peptide chemistry

    Native Chemical Ligation–Photodesulfurization in Flow

    Timothy S. Chisholm, Daniel Clayton, Luke J. Dowman, Jessica Sayers, Richard J. Payne

    • School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia
    View abstract

    γ-Glutamyl-dipeptides: Easy tools to rapidly probe the stereoelectronic properties of the ionotropic glutamate receptor binding pocket

    Lucia Tamborinia, Veronica Nicosiaa, Paola Contia, Federica Dall'Oglioa, Carlo De Michelia, Birgitte Nielsenb, Anders A. Jensenb, Darryl S. Pickeringb, Andrea Pintoa

    • a Department of Pharmaceutical Sciences (DISFARM), University of Milan, Via Mangiagalli 25, 20133 Milan, Italy
    • b Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen OE, Denmark
    View abstract

    A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols

    Ian R. Baxendale, Steven V. Ley, Christopher D. Smith, Geoffrey K. Tranmer

    • Innovative Technology Centre, Cambridge, UK
    View abstract

    Application Notes regarding Peptide chemistry

    No related applications found.

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