Application Note 45 – Selective oxidation using 50% aqueous hydrogen peroxide

This new application note demonstrates the oxidation of thioanisole using hydrogen peroxide in continuous flow. It highlights the use of 50 wt% aqueous hydrogen peroxide which can be pumped neat with Vapourtec systems. Both cooled and heated conditions are explored for this exothermic reaction.  The reaction temperature was controlled using a Vapourtec cooling module for the sub-ambient conditions.  To explore the highest possible throughput, mildly heated conditions were also explored.