Green chemistry

    Green chemistry, also known as sustainable chemistry, is a collection of practices guided by the twelve principles of green chemistry that aim to design chemical products and processes to reduce their environmental impact.

    The twelve principles of green chemistry, which cover all areas of chemistry and chemical engineering, apply to the life-cycle of a chemical product from production to disposal. Using the green chemistry approach, products and their manufacture are designed to reduce the need for and production of hazardous substances and energy intensive processes.

    The principles of green chemistry cover all stages of production to minimise the overall impact of a product, beginning from designing products that are non-hazardous and are synthesised from renewable feedstock reagents, to processes that use non-hazardous solvents and low energy production strategies. The principles of green chemistry use a “prevention is better than cure” philosophy; by not creating environmentally hazardous materials, the need to process and clean them is removed, improving the overall efficiency of the process and thus reducing the environmental impact of the specific chemical product.

    Technology enabling green chemistry

    Flow chemistry is ideally suited to meeting the principles of green chemistry; processes are inherently safer with small reaction volumes and lower volumes of solvents and reagents needed. There is low risk of environmental exposure to reagents, and processes can be scaled without the need for re-optimisation.

    Solvent selection for green chemistry


    Examples of published literature for Green chemistry

    A convenient, mild and green synthesis of NH-sulfoximines in flow reactors

    Leonardo Degennaro1, Arianna Tota1, Sonia De Angelis1, Michael Andresini1, Cosimo Cardellicchio2, Maria Annunziata Capozzi1, Giuseppe Romanazzi3, Renzo Luisi1

    • 1 University of Bari, Department of Pharmacy - Drug Sciences, Bari, Italy
    • 2 CNR ICCOM, Department of Chemistry, Bari, Italy
    • 3 Politecnico di Bari, DICATECh, Bari, Italy
    View abstract

    Efficient synthesis of 5-(chloromethyl) furfural (CMF) from high fructose corn syrup (HFCS) using continuous flow processing

    T. M. Kohla, B. Bizeta, P. Kevana, C. Sellwooda, J. Tsanaktsidisa, C. H. Hornunga

    • a CSIRO Manufacturing Flagship, Bag 10, Clayton South, Australia
    View abstract

    The Preparation of Ethyl Levulinate Facilitated by Flow Processing: The Catalyzed and Uncatalyzed Esterification of Levulinic Acid

    Meghan P. Negus1, Andrew C. Mansfield2, Nicholas E. Leadbeater1

    • 1 Department of Chemistry, University of Connecticut, 55 North Eagleville Road, Storrs, CT 06269, United States
    • 2 Vapourtec Ltd., Park Farm Business Centre, Bury St. Edmunds IP28 6TS, United Kingdom
    • 3 Department of Community Medicine and Health Care, University of Connecticut Health Center, The Exchange, 263 Farmington Ave, Farmington, CT 06030, United States
    View abstract

    Flow synthesis of a versatile fructosamine mimic and quenching studies of a fructose transport probe

    Matthew B. Plutschack1,2, D. Tyler McQuade1,2, Giulio Valenti2, Peter H. Seeberger2, 1Department of Chemistry and Biochemistry, Florida State University, USA, 2Max Planck Institute of Colloids and Interfaces, Germany

    View abstract

    Continuous-flow generation of diazoesters and their direct use in S-H and P-H insertion reactions: synthesis of a-sulfanyl, a-sulfonyl and a-phosphono carboxylates

    Hannah E. Bartrum1, David C. Blakemore2, Christopher J. Moody1, Christopher J. Hayes1

    • 1School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    • 2Pfizer Neusentis, The Portway Building, Granta Park, Cambridge, CB21 6GS, UK
    View abstract

    Application Notes regarding Green chemistry

    No related applications found.

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