Date: 11 December 2014 | Category: News
Flow chemistry systems designed and manufactured by Suffolk (UK) based Vapourtec have recently reached the impressive milestone of having been cited in 150 peer review publications. By way of a comparison Vapourtec’s two closest competitors in flow chemistry technology have been mentioned in 51 and 40 publications respectively.
Date: 03 December 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the Max-Planck Institute of Chemistry and Biology have developed an approach to deliver a range of active pharmaceutical ingredients (API’s) in a continuous process. The concept uses a non-iterative chemical assembly system that uses a range of flow chemistry modules that can be linked and interchanged to gain access to an increased chemical space.
Date: 03 December 2014 | Category: News
Using the Vapourtec E-Series flow chemistry system researchers from the Ludwig-Maximilians-Universitat Munchen have shown a procedure for functionalizing a range of heterocycles and various sensitive acrylates using the strong, non-nucleotide Knochel-Hauser base TMPMgCl.LiCl and the subsequent quenching with various electrophiles. The ability of the advanced Vapourtec V-3 pump to continuously process reagents of this type allows for the multi-gram scale-up of these reactions previously limited to small scale.
Date: 01 November 2014 | Category: News
This article will outline a few of the most common types of photochemical reaction and analyse the key features of a reactor, considering the light sources currently available. Finally, it will showcase just a few of the many real world applications for photochemistry.
Date: 14 October 2014 | Category: News
Recently published research into the production of Metal-Organic Frameworks (MOFs) utilising Vapourtec flow chemistry technology has revealed the substantial benefits of adopting a continuous flow process over the traditional batch approach. MOFs exhibit similar structures to naturally occurring Zeolites however their properties can be synthetically tuned providing a multitude of potential industrial applications including the storage, separation and triggered release of gases, drug molecules or toxins due to the porous nature of MOF compounds.
Date: 07 October 2014 | Category: News
The incredibly powerful potential of photochemistry is revealed in four application notes recently posted by Suffolk-based flow chemistry engineering firm Vapourtec. The four application notes cover ‘Synthesis of Artemisinin using E-Series and UV-150 reactor’ (Application Note 39), ‘α-Photodecarboxylation of Phthaloyl Glycine’ (38), ‘Photochemical Transformation of Methyl Coumalate’ (37) and ‘[2+2] Photocycloaddtion of Maleimide and 1-Hexyne’ (36).
Date: 24 September 2014 | Category: News
There are a number of key advantages of a continuous flow approach to photochemistry over a traditional batch method including consistent light penetration, controlled exposure times, precise temperature control and easy scalability as well as the removal of photochemical products from the irradiated area. Comparing the two methods when it comes to the Photochemical Transformation of Methyl Coumalate reveals the substantial efficiencies and economies that can be accrued from the flow chemistry route.
Date: 17 September 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the Max-Planck Institute of Colloids and Interfaces have developed an inexpensive, large scale synthesis of a range of anti-Malaria drugs under continuous flow conditions. The continuous, divergent synthesis system is coupled to continuous purification and is capable of producing four anti-malarial APIs.
Date: 08 September 2014 | Category: News
UK chemistry engineering firm Vapourtec is establishing a burgeoning market for its flow chemistry systems across India with the continued development of a distribution partnership with Mumbai-based Pi-Process Intensification. Pi-Process Intensification have been acting as distributors for Vapourtec’s R-Series systems for the past three years and will now also be distributing their E-Series system.
Date: 05 September 2014 | Category: News
Using the Vapourtec R-Series the Vapourtec R-Series flow chemistry system researchers from the Universita di Perugia, the Universita degli Studi di Napoli Federico II and TES Pharma have shown the continuous flow multi-gram synthesis of Thien[2,3-c]isoquinolin-5(4H)-one (TIQ) an …
Date: 27 August 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the Institut de Chemie des Substances Naturelles and the Institut des Sciences Moleculaires (CNRS) have shown the efficient and highly selective glycosylation of peracetylated β-D-N-acetyl gluco and galactosamin…
Date: 10 August 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the UCB Biopharma have shown the development and preparation of an improved synthesis of 2-substituted 1,2,3-triazoles over conventional batch processes. Using the advantages of flow chemistry the group were able to scale up the process that involved the use of hazardous diazonium intermediates, dissolved ammonia and a novel catalytic copper oxidative cyclisation.
Date: 30 July 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the Centre for Sustainable Chemical Technologies at the University of Bath have shown the development, preparation and use of two novel polymer encapsulated silica supported palladium catalysts for cross coupling reactions which were shown to be highly reactive, robust of reusable.
Date: 23 July 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the Max-Planck Institute for Colloids and Interfaces have shown a process were primary and secondary amines can be oxidised quantitatively using singlet oxygen to the corresponding imine. This chemistry developed by the group at Max-Planck again shows the innovative use of continuous photochemistry for efficient chemical transformations.
Date: 04 June 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from Janssen Research and Development (Spain), the University of Leuven and the Universidad de Castilla-La Macncha have shown a continuous flow process for carbonylation reactions without the need of toxic carbon monoxide gas and have shown new chemical reactivity under flow conditions that were not previously possible under batch conditions.
Date: 28 May 2014 | Category: News
Using the Vapourtec R-Series flow chemistry system researchers from the Department of Chemistry at the University of Cambridge and the Institut fur Organische Chemie at Leibniz Universitat Hannover have discovered new chemical reactivity patterns under flow conditions that were n…
Date: 27 May 2014 | Category: News
Two of the world’s leading flow chemistry systems as well as the latest addition to the field of photochemistry technology will be on show at Chemspec Europe on 18-19 June and IMRET (Conference on Microreaction Technology) 23-25 June. Both events take place in Budapest, Hungary…
Date: 24 May 2014 | Categories: Headline News, News
Vapourtec has developed the UV-150, a pioneering photochemical reactor that will lead to more efficient, precise, consistent, safe and scalable photochemical synthesis offering potential routes for novel compounds and building blocks together with possible new manufacturing processes.
Date: 23 May 2014 | Categories: Headline News, News
Scientists at the Max Planck institute have unveiled a breakthrough synthesis method for the drug Artimesinin that could make effective malaria treatment affordable for > 200 million worldwide sufferers.
The synthesis uses a Vapourtec flow chemistry system and a photo reactor.
Date: 09 April 2014 | Categories: Headline News, News
Vapourtec has reached the notable landmark of appearing in 125 peer reviewed publications, making Vapourtec the clear leader in terms of research breakthroughs and published findings for flow chemistry systems.
Date: 02 April 2014 | Categories: Headline News, News
Vapourtec’s R-Series flow chemistry system has played its part in another significant breakthrough with the development in Australia of a brand new sun cream based on mimicking the natural protection to sunlight created by coral in the Great Barrier Reef.
Date: 17 February 2014 | Category: News
Chemistry engineering specialists Vapourtec (Suffolk, UK) has seen its flagship R-Series flow chemistry system reach a notable milestone with global sales recently reaching the 200 mark. The R-Series has a wide range of applications and is already used around the world by many major companies including BP, Pfizer, GSK, Sanofi, Novartis and Johnson & Johnson.
Date: 13 December 2013 | Categories: Headline News, News
Vapourtec (Suffolk, UK) has recently signed a pioneering, 3 year agreement with Nanjing University of Technology (NJUT) in China to establish a joint research centre in the fast growing, hi-tec field of flow chemistry.
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.
