The following (non-exhaustive) list of papers shows peer-reviewed work that has been published using the Vapourtec R-Series and E-Series flow chemistry systems. As new work is continually published, please check here for updates.
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Flow reactors for Solid phase synthesis (SPS) have gained attention, as they appear to be more efficient than the widely used stirred tanks. In either Packed Bed (PBR) or Loose Bed Reactors (LBR) configurations, the theoretical description of such platforms is limited. This study...
This work presents a significantly improved and scaled continuous flow process for the synthesis of Propofol (2,6-diisopropylphenol), a WHO-essential anaesthetic agent. Building upon previous research, the two-step synthesis featuring a Friedel-Crafts bisalkylation of 4-hydroxybe...
Chroman-2-one derivatives are biologically relevant structures that present interesting pharmacological and biological properties, being the C-4 alkylated derivatives of particular interest. The methods described in the literature allow the C-4 functionalization of coumarins with...
The design of flow reactors for heterogeneous photocatalysis is key to enhancing the control, efficiency, and scalability of chemical reactions. However, conventional designs such as slurry reactors and fixed bed reactors often suffer from poor light penetration, challenging cata...
The use of novel UV-C LEDs emitting monochromatic light at 265 nm is reported for the continuous flow synthesis of ketenimines from isoxazoles. The resulting flow process is compared to the use of a traditional Hg-lamp showing that substantial improvements in reaction performance...