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Products

E-Series

The E-Series Flow Chemistry System

The E-Series is a robust system which allows pumping strong/concentrated acids/bases, light slurries/suspensions and sensitive reagents. Each E-Series includes V-3 pumps and an easy to use software ideal for any flow chemist.

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R-Series

The R-Series modular flow chemistry system

The Vapourtec R-Series is undoubtedly the most versatile, modular flow chemistry system available today. It offers best in class performance, is easy to learn and can be adapted for a large variety of reactions or processes.

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News

Library Synthesis of Dynamin GTPase Inhibitors

Authors: Andrew J. S. Lin, Nicholas S. O’Brien, Abigail Florence, Matthew Killen, Shelby L. Frailey, Jayne Gilbert, Jennette A. Sakoff, Mohammed K. Amin, Emily E. Castelloe, Ngoc Chau, Jing Xue, Phillip J. Robinson, and Adam McCluskey* The McClusky group at the University of Newcastle in New South Wales, Australia, has used the Vapourtec E-Series easy-MedChem system in the synthesis of a library of substituted […]

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Flow lithiation for production of crisaborole

Authors: Chander Singh Bohara, Manjinder Singh Phull, and Srihari Pabbaraja* The Pabbaraja group at the CSIR-Indian Institute of Chemical Technology, Hyderabad, India has used the Vapourtec R-Series to prepare crisaborole, a boron-containing phosphodiesterase inhibitor, on multigram scale.[1] The use of a flow-based approach improved yields over the established batch procedure by 50%, which was attributed to more precise control of the reaction kinetics and thermal regulation during n-BuLi addition. Scheme 1: A continuous flow approach provided crisaborole over […]

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Selective Synthesis of trans-A₂B₂ Porphyrins

Synthetic Pathway to trans-A2B2‑Porphyrins: From Oxime-Substituted Dipyrromethanes to Functionalized Macrocycles Authors: João C. S. Simões, Bruna D. P. Costa, Ana Clara B. Rodrigues, Susana M. M. Lopes, J. Sérgio Seixas de Melo, Marta Pineiro, and Teresa M. V. D. Pinho e Melo Researchers from the group led by Teresa M. V. D. Pinho e Melo […]

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