Date: 16 June 2022 | Category: News
Vapourtec will be attending and presenting at the 3rd edition of the International OligonucIeotides and Peptides Conference (IOPC 2022) due to be held in Milan later this month (27-29 June).
Vapourtec chemist, Victoire Laude, will be delivering a talk titled “Modern peptide synthesis – Applying real-time monitoring to improve synthesis’ efficiency” at 10.30am on Wednesday 29th. The event will highlight key developments and breakthroughs within oligonucleotide and peptide therapeutics and will also feature a number of speeches from key industry individuals.
Victoire explained: “My presentation describes the key achievements in Vapourtec’s work towards gaining benefit from continuous flow SPPS (CF-SPPS) using Glucagon-like peptide-1 (GLP-1) as example peptide. GLP-1 is a 30-mer peptide the basis for a class of medications used to treat type 2 diabetes. Coupling conditions and anti-racemisation strategies were optimized, as well as cleavage in flow, yielding a crude purity of over 80%. Pumping a TFA cocktail at 50°C has allowed the peptide to be cleaved in under 40 minutes, obtaining repeatable results.”
For more details about the conference click here
For more details about Vapourtec’s systems for peptide synthesis click here