Photocatalytic and Photoinduced Phosphonylation of Aryl Iodides: A Batch and Flow Study

Herein we disclose our study toward the synthesis of aryl phosphonates using either photocatalytic conditions or a photoinduced process. First, a phosphonylation reaction catalyzed by a copper complex was developed in batch, but unfortunately, it was not efficient under continuous flow. Alternatively, a photoinduced phosphonylation reaction was developed in continuous flow with a moderate efficiency. Finally, to enhance the yields observed under the continuous flow conditions for the scale-up, a complementary approach using another commercially available photoreactor was suggested to tackle the modest productivity observed in continuous flow.

• Lapierre, R
• Le, T
• Schiavi, B
• Thevenet, D
• Bazin, M
• Buzdygon, R
• Jubault, P
• Poisson, T

• Normandie Univ, INSA Rouen, UNIROUEN, CNRS, COBRA (UMR 6014), 76000 Rouen, France

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