Metal-free [2+2]-photocycloaddition of unactivated alkenes enabled by continuous flow processing

We report a continuous flow approach generating bicyclic cyclobutanes from unactivated alkenes in a metal-free manner that is inspired by the Kochi-Salomon reaction. A filtered Hg-lamp in combination with a simple flow set-up and acetone as UV light-absorbing co-solvent are crucial for this method thus showcasing attractive features for further exploitations.

• O'Hanlon, D
• Davin, S
• Glennon, B
• Baumann, M

• APC Ltd, Cherrywood Business Park, Loughlinstown, Co., Dublin, D18 DH50, Ireland

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