Electrochemical Cyclopropanation of 1, 3-Dialkyl Bromides

Added on:
1 Jan, 2024

An electrochemical synthesis of mono- and 1,1-disubstituted cyclopropanes has been demonstrated. Readily available 1,3-dialkyl bromides were used as starting materials, and the method was enabled by the incorporation of a sacrificial reductant along with cost-effective cathode and anode materials. The need for a divided cell and the use of hazardous or expensive electrodes were eliminated, facilitating the adaptation of the protocol to a continuous flow system. Additionally, an alternative protocol employing a simple sacrificial anode was described.

  • Charvet, S
  • Jacob, C
  • Dietsch, A
  • Tintori, G
  • Echeverria, P
  • Vantourout, J
  • CNRS, INSA, CPE-Lyon, ICBMS, UMR 5246, Bâtiment LEDERER, Univ Lyon, Université Lyon 1, 1 rue Victor Grignard, 69622 Villeurbanne Cedex, France
Electrochemical Cyclopropanation of 1
Read the publication that featured this abstract