Application Note 51 – Palladium on Charcoal Slurries in Continuous Flow Hydrogenation

Using a Vapourtec E-Series with V-3 peristaltic pumps it has been possible to handle solids in flow, to perform a continuous flow hydrogenation of 4-(2-fluoro-4-nitrophenyl)morpholine to the Linezolid intermediate 3-fluoro-4-(4-morpholinyl)aniline, using ammonium formate, and a heterogeneous palladium on charcoal slurry.
Join the Vapourtec Knowledge Base to access this Application noteGet in touch
For more information on flow chemistry systems and services please use the contact methods below.
Call us on +44 (0)1284 728659 or Email us