Aromatic Nitration with fuming nitric acid

This Application Note illustrates how a Vapourtec acid resistant R Series flow chemistry system (with acid resistant pumps, sensors, connectors, tubing and back pressure regulator) was used to pump highly corrosive, fuming nitric acid and determine optimal flow-through conditions suitable for a scale-up nitration of an aromatic starting material, all in a period of 3 days.

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