Visible‐Light‐Mediated Cross‐Couplings and C–H Activation via Dual Photoredox/Transition‐Metal Catalysis in Continuous‐Flow Processes
- Soo Dong Kim
- Jonghyun Lee
- Nam-Jung Kim
- Boyoung Park
- Kyung Hee University, Department of Pharmacy, Kyungheedaero 26, 02447 Seoul, Republic of KoreaRead the publication that featured this abstract
Here we review dual photoredox/transition‐metal catalysis for C–C/C–N cross‐couplings and C–H activation in continuous‐flow processes. Compared to conventional transition‐metal catalysis for these reactions, a visible‐light‐mediated synergistic catalysis enables the use of relatively mild and environmentally friendly reaction conditions by decreasing the activation energy and using a renewable energy source. However, photochemical transformations in batch processing have limitations such as reactivity, reaction time, substrate scope, and scalability due to light attenuation as represented by the Beer‐Lambert law. In this review article, we therefore summarize and discuss several examples of cross‐couplings and C–H activation in continuous‐flow processes that overcome these problems in batch processing.
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible |
- Precise |
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust |
- Easy to use |
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.