Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
- Swapna S. Mohapatraa,b
- Zoe E. Wilsona
- Sujit Royb
- Steven V. Leya
- a Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK
- b Organometallics & Catalysis Laboratory, School of Basic Sciences, Indian Institute of Technology, Bhubaneswar 751013, IndiaRead the publication that featured this abstract
Flow chemistry enables the preparation of bis(indolyl)methanes from various indoles and structurally divergent aldehydes using Sc(OTf)3 catalysis. The reaction is regioselective for C-3 functionalization of the indoles, occurring over short reaction times allowing for rapid investigation of scope with straightforward work up facilitating product isolation.
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust :
- Easy to use :
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.