Sustainable flow synthesis of a versatile cyclopentenone building block
- Marcus Baumann†
- Ian R. Baxendale†
- Paolo Filipponi‡
- Te Hu†
- † Department of Chemistry, University of Durham, South Road, DH1 3LE Durham, U.K
- ‡ Novartis Pharma AG, Fabrikstrasse 14, 4002 Basel, SwitzerlandRead the publication that featured this abstract
A flow based multistep processing sequence to reliably provide the delivery of a highly functional cyclopentenone is described. The exemplification of employing solid dosing of reagents and in-line aqueous extraction has enabled an integrated workflow in a highly automated reactor setup.
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