A solid-supported arylboronic acid catalyst for direct amidation

• Yihao Du^a,
• Thomas Barber^a,
• Sol Ee Lim^a,
• Henry S. Rzepa^b,
• Ian R. Baxendale^*a,
• Andrew Whiting^*a,

• ^a Centre for Sustainable Chemical Processes, Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, UK
• ^a Department of Chemistry, Imperial College, South Kensington Campus, London, UK

An efficient heterogeneous amidation catalyst has been prepared by co-polymerisation of styrene, DVB with 4-styreneboronic acid, which shows wide substrate applicability and higher reactivity than the equivalent homogeneous phenylboronic acid, suggesting potential cooperative catalytic effects. The catalyst can be easily recovered and reused; suitable for use in packed bed flow reactors.

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