A solid-supported arylboronic acid catalyst for direct amidation

    • Yihao Dua,
    • Thomas Barbera,
    • Sol Ee Lima,
    • Henry S. Rzepab,
    • Ian R. Baxendale*a,
    • Andrew Whiting*a,
    • a Centre for Sustainable Chemical Processes, Department of Chemistry, Durham University, Science Laboratories, South Road, Durham, UK
    • a Department of Chemistry, Imperial College, South Kensington Campus, London, UK

    An efficient heterogeneous amidation catalyst has been prepared by co-polymerisation of styrene, DVB with 4-styreneboronic acid, which shows wide substrate applicability and higher reactivity than the equivalent homogeneous phenylboronic acid, suggesting potential cooperative catalytic effects. The catalyst can be easily recovered and reused; suitable for use in packed bed flow reactors.

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