Reductive aminations using a 3D printed supported metal(0) catalyst system
- Charlotte Genet1
- Xuan Nguyen1
- Bita Bayatsarmadi2
- Mike D. Horne2
- James Gardiner1
- Christian H. Hornung1
- 1 CSIRO Manufacturing, Clayton, South Australia
- 2 CSIRO Minerals Resources, Clayton, South AustraliaRead the publication that featured this abstract
Additively manufactured catalytic static mixers were used for the intensified reductive amination of aldehydes and ketones inside a continuous flow reactor. This efficient synthesis method is enabled by the use of tubular reactors fitted with 3D printed metal static mixers which are coated with a catalytically active layer, either Pd or Ni. The 3D printing process allows for maximum design flexibility for the mixer scaffold and is compatible with a range of deposition methods including electroplating and metal cold spraying. Single- and multi-stage continuous flow processing yielded high to full conversion and has the potential to scale-up these operations without the need for manual handling of reactive imine intermediates.
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