The rapid generation of isothiocyanates in flow
- Marcus Baumann
- Ian R. Baxendale
- Department of Chemistry, University of Durham, U.K.
Read the publication that featured this abstractIsothiocyanates are versatile starting materials for a wide range of chemical reactions. However, their high nucleophilic susceptibility means they are best prepared and used immediately. We report here on a flow platform for the fast and efficient formation of isothiocyanates by the direct conversion of easily prepared chloroximes. To expedite this chemistry a flow insert cartridge containing two immobilised reagents is used to affect the chemical transformation which typically eliminates the requirements for any conventional work-up or purification of the reaction stream.
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R-Series

The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
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- Automatable
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
E-Series

The Vapourtec E-Series is the perfect introductory system for flow chemistry
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The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.