Phase-Transfer Catalysis under Continuous Flow Conditions: An Alternative Approach to the Biphasic Liquid/Liquid O-Alkylation of Phenols

O-Alkylation of phenol compounds was performed in a continuous flow apparatus under biphasic liquid/liquid conditions and promoted by tetrabutylammonium bromide (TBAB) as a phase-transfer catalyst. The segmented flow that is generated within the flow system is able to afford the desired ethers in high yield and in very short times.

• Daniele De Zani²
• Matteo Colombo¹

• ¹NiKem Research 20021 via Zambeletti 25 Milan Baranzate Italy
• ²Erregierre, San Paolo D'Argon Bergamo Italy

• Request a Brochure
• Request more Info
• Request a Quote