KMnO4-Mediated Oxidation as a Continuous Flow Process

    • Jorg Sedelmeier
    • Steven V. Ley
    • Ian R. Baxendale
    • Marcus Baumann
    • Innovative Technology Centre, University of Cambridge

    An efficient and easily scalable transformation of alcohols and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and carboxylic acids using permanganate as the oxidant within a continuous flow reactor is reported. Notably, the generation and downstream processing of MnO2 slurries was not found to cause any blocking of the reactor when ultrasound pulses were applied to the flow system.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us

    Request a quote