Efficient metal-free photochemical borylation of aryl halides under batch and continuous-flow conditions
Kai Chen, Shuai Zhang, Pei He, Pengfei Li *
- Center for Organic Chemistry, Frontier Institute of Science and Technology (FIST), Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an, Shaanxi 710054, ChinaRead the publication that featured this abstract
A rapid, chemoselective and metal-free C–B bond-forming reaction of aryl iodides and bromides in aqueous solution at low temperatures was discovered. This reaction is amenable to batch and continuous-flow conditions and shows exceptional functional group tolerance and broad substrate scope regarding both the aryl halide and the borylating reagent. Initial mechanistic experiments indicated a photolytically generated aryl radical as the key intermediate.
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible :
- Precise :
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust :
- Easy to use :
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.