Effect of phase transfer chemistry, segmented fluid flow, and sonication on the synthesis of cinnamic esters

    • Mauro Riccaboni
    • Elena La Porta
    • Andrea Martorana
    • Roberta Attanasio
    • Department of Medicinal Chemistry, NiKem Research Srl, Milan, Italy

    Wittig reaction under Phase Transfer conditions was performed in a flow reaction system. Different bases, aldehydes, phosphonium salts, and flow reaction parameters were investigated, in absence of a phase transfert catalyst. An improvement of the reaction outcome (yield and reaction time) was achieved through the immersion of the reactor into an ultrasound bath

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us