Decarboxylative biaryl synthesis in a continuous flow reactor
- 1Paul P. Lange
- 1Lukas J. Gooßen
- 2Philip Podmore
- 2Toby Underwood
- 2Nunzio Sciammetta
- 1Technische Universität Kaiserslautern, Germany
- 2Pfizer Global R&D, Sandwich, UKRead the publication that featured this abstract
A practical protocol was developed that allows performing decarboxylative cross-coupling reactions in continuous flow reactors. Various biaryls were thus synthesized from aromatic carboxylic acids and aryl triflates using a Cu/Pd-catalyst system.
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible :
- Precise :
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust :
- Easy to use :
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.