Decarboxylative biaryl synthesis in a continuous flow reactor
- 1Paul P. Lange
- 1Lukas J. Gooßen
- 2Philip Podmore
- 2Toby Underwood
- 2Nunzio Sciammetta
- 1Technische Universität Kaiserslautern, Germany
- 2Pfizer Global R&D, Sandwich, UKRead the publication that featured this abstract
A practical protocol was developed that allows performing decarboxylative cross-coupling reactions in continuous flow reactors. Various biaryls were thus synthesized from aromatic carboxylic acids and aryl triflates using a Cu/Pd-catalyst system.
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