Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin

    • François Lévesque1
    • Peter H. Seeberger1,2
    • 1Department for Biomolecular Systems, Max-Planck Institute for Colloids and Interfaces, Germany
    • 2Institute for Chemistry and Biochemistry, Freie Universität Berlin, Germany

    Malaria is a serious global health issue. Artemisinin combination treatments are the first-line drugs, but supplies are limited because artemisinin is obtained solely by extraction from Artemisia annua. A continuous-flow process that converts dihydroartemisinic acid into artemisinin (see scheme) was shown to be an inexpensive and scalable process that can ensure a steady, affordable supply of artemisinin.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us