Continuous Flow Synthesis of Organic Electronic Materials : Case Studies in Methodology Translation and Scale-up

The continuous flow synthesis of functional thiophene derivatives was examined. Methodology for the lithiation of thiophene building blocks was developed using a commercial bench-top flow reactor. In addition, the advantages of flow processing were demonstrated in the synthesis of a high performance organic dye in gram scale.

• Helga Seyler¹
• Stefan Haid²
• Tae-Hyuk Kwon¹
• David J. Jones¹
• Peter Bäuerle²
• Andrew B. Holmes¹
• Wallace W. H. Wong^1*

• ¹Bio21 Institute, University of Melbourne, Australia.
• ²Institute of Organic Chemistry II and Advanced Materials, University of Ulm, Germany.

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