Continuous Flow Synthesis of Organic Electronic Materials : Case Studies in Methodology Translation and Scale-up
- Helga Seyler1
- Stefan Haid2
- Tae-Hyuk Kwon1
- David J. Jones1
- Peter Bäuerle2
- Andrew B. Holmes1
- Wallace W. H. Wong1*
- 1Bio21 Institute, University of Melbourne, Australia.
- 2Institute of Organic Chemistry II and Advanced Materials, University of Ulm, Germany.Read the publication that featured this abstract
The continuous flow synthesis of functional thiophene derivatives was examined. Methodology for the lithiation of thiophene building blocks was developed using a commercial bench-top flow reactor. In addition, the advantages of flow processing were demonstrated in the synthesis of a high performance organic dye in gram scale.
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