Continuous Flow Palladium(II)-Catalyzed Oxidative Heck Reactions with Arylboronic Acids
- Luke R. Odell1
- Jonas Lindh1
- Tomas Gustafsson2
- Mats Larhed1*
- 1Organic Pharmaceutical Chemistry, Department of MedChem, Uppsala University, Sweden
- 2AstraZeneca R&D Mölndal, SwedenRead the publication that featured this abstract
Palladium(II)-catalyzed oxidative Heck reactions were investigated under continuous flow conditions. Selective, fast and convenient protocols for the coupling of arylboronic acids with electron-rich and electron-poor olefins were developed by using a commercially available flow reactor.
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