An Integrated Flow and Batch-Based Approach for the Synthesis of O-Methyl Siphonazole
- Marcus Baumann
- Ian R. Baxendale
- Malte Brasholz
- John J. Hayward
- Steven V. Ley
- Nikzad Nikbin
- Innovative Technology Centre, Cambridge, UKRead the publication that featured this abstract
The bisoxazole containing natural product O-methyl siphonazole was assembled using a suite of microreactors via a flow-based approach in concert with traditional batch methods. The use of a toolbox of solid-supported scavengers and reagents to aid purification afforded the natural product in a total of nine steps.
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