Amination of Aryl Halides and Esters Using Intensified Continuous Flow Processing

    Thomas M. Kohl *, Christian H. Hornung, John Tsanaktsidis

    • CSIRO Manufacturing Flagship, Bag 10, Clayton South, Victoria 3169, Australia

    Significant process intensification of the amination reactions of aryl halides and esters has been demonstrated using continuous flow processing. Using this technology traditionally difficult amination reactions have been performed safely at elevated temperatures. These reactions were successfully conducted on laboratory scale coil reactor modules with 1 mm internal diameter (ID) and on a preparatory scale tubular reactor with 6 mm ID containing static mixers.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us

    Request a quote