A simple setup for transfer hydrogenations in flow chemistry

Added on:
6 May, 2016

By using a packed-bed reactor with a palladium charcoal catalyst and ammonium formate or triethylsilane as hydrogen/hydride source, various functional groups including nitro groups, azides and alkenes can be efficiently reduced by a transfer hydrogenation process under mild conditions in a simple flow system.

  • Matthew Hutchings
  • Thomas Wirth*
  • School of Chemistry, Cardiff University, Cardiff CF10 3AT, UK
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