Home > Resource Centre > Publications > A modular flow reactor for performing Curtius rearrangements as a continuous flow process
A modular flow reactor for performing Curtius rearrangements as a continuous flow process
- Marcus Baumann1
- Ian R. Baxendale1
- Steven V. Ley1
- Nikzad Nikbin1
- Christopher D. Smith1
- Jason P. Tierney2
- 1Innovative Technology Centre, Department of Chemistry, University of Cambridge
- 2Neurology Lead Discovery Chemistry, GlaxoSmithKline R and D, Harlow, UK
Read the publication that featured this abstractThe use of a mesofluidic flow reactor is described for performing Curtius rearrangement reactions of carboxylic acids in the presence of diphenylphosphoryl azide and trapping of the intermediate isocyanates with various nucleophiles.
Get in touch
For more information on flow chemistry systems and services please use the contact methods below.
Call us on +44 (0)1284 728659 or Email us
Resource Centre
R-Series

The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible |
- Precise |
- Automatable
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
E-Series

The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust |
- Easy to use |
- Affordable
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.