A Flow Process Using Microreactors for the Preparation of a Quinolone Derivative as a Potent 5HT1B> Antagonist
- Zizheng Qian
- Ian R. Baxendale
- Steven V. Ley
- Innovative Technology Centre, Department of Chemistry, University of CambridgeRead the publication that featured this abstract
This article describes the continuous flow synthesis of 6-methoxy-8-(4-methyl-1,4-diazepan-1-yl)-N-(4-morpholinophen-yl)-4-oxo-1,4-dihydroquinoline-2-carboxamide, a potent 5HT1B antagonist developed by AstraZeneca.
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