A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly

Added on:
24 Mar, 2006

A flow process for the multi-step synthesis of the alkaloid natural product (±)-oxomaritidine is described, mediated through the use of microfluidic pumping systems that progress material through various packed columns containing immobilized reagents, catalysts, scavengers or catch and release agents; our route involves the combination of seven separate synthetic steps linked into one continuous sequence utilizing flow chemistry.

  • Ian R. Baxendale
  • Jon Deeley
  • Charlotte M. Griffiths-Jones
  • Steven V. Ley
  • Steen Saaby
  • Geoffrey K. Tranmer
  • Innovative Technology Centre, University of Cambridge
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