A continuous-flow synthesis of annulated and polysubstituted furans from the reaction of ketones and a-haloketones

    • Mark York
    • CSIRO Materials Science and Engineering, Australia
    • Cooperative Research Centre for Polymers, Notting Hill, Australia

    A synthesis of di-, tri- and tetra-substituted furans from reaction of the corresponding ketones and α-haloketones with LiHMDS is reported. Reaction under continuous-flow conditions gave increased yields and removed the need for external cooling when compared to the unoptimised batch conditions.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us

    Request a quote