The following (non-exhaustive) list of papers shows peer-reviewed work that has been published using the Vapourtec R-Series and E-Series flow chemistry systems. As new work is continually published, please check here for updates.
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Sulfoximines have emerged as versatile scaffolds in modern synthesis, medicinal chemistry, and catalysis due to their tunable electronic and steric properties. In particular, N-aroyl sulfoximines are valuable intermediates in amide coupling, C-H functionalization, and heterocycle...
A scalable flow electrochemical platform achieves up to 9.2 g/h productivity at a 100 g scale using an innovative three-electrode reactor design. Dual-sided cathodes enable 16 parallel channels across eight modules, maintaining 1 min residence time without reoptimization. The met...
A robust and inherently safer continuous flow process has been developed for the synthesis of DABCYL azo fluorescent quenchers. The conventional diazotization azo coupling sequence was successfully translated from hazardous batch conditions to a controlled multistep flow process,...
We report a zinc (d)-tartrate catalyzed asymmetric ring opening of epoxides with thiols, affording β-hydroxy sulfides with high enantioselectivity up to 98:2 er after crystallization. The process enables fast reaction in 10–15 min under continuous flow conditions and demonstra...
Triazoline and aziridine derivatives were synthesised by diastereo- and regioselective Huisgen cycloaddition of 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl azide with ethyl 4,4,4-trifluorocrotonate. Use of a continuous-flow reactor led to reduced reaction time and enabled use of...
