Flow Chemistry as a Drug Discovery Tool: A Medicinal Chemistry Perspective

    Andrew R. Bogdan1, Michael G. Organ2

    • 1 Discovery Chemistry and Technology, AbbVie Inc., North Chicago, USA
    • 2 Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada

    The applications of flow chemistry in a drug discovery environment are discussed within. The development of integrated synthesis–bioassay platforms is discussed in the context of enabling medicinal chemistry programs, as is the use of flow chemistry to facilitate intermediate scale-up in a lead optimization setting. Emerging chemical technologies are also discussed, highlighting the use of high temperatures, hazardous gases, and photochemistry in flow to support medicinal chemistry efforts.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us