Flow Chemistry as a Drug Discovery Tool: A Medicinal Chemistry Perspective
Andrew R. Bogdan1, Michael G. Organ2
- 1 Discovery Chemistry and Technology, AbbVie Inc., North Chicago, USA
- 2 Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada
Read the publication that featured this abstractThe applications of flow chemistry in a drug discovery environment are discussed within. The development of integrated synthesis–bioassay platforms is discussed in the context of enabling medicinal chemistry programs, as is the use of flow chemistry to facilitate intermediate scale-up in a lead optimization setting. Emerging chemical technologies are also discussed, highlighting the use of high temperatures, hazardous gases, and photochemistry in flow to support medicinal chemistry efforts.
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R-Series

The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
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The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
E-Series

The Vapourtec E-Series is the perfect introductory system for flow chemistry
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The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.