Flow assisted synthesis: a key fragment of SR 142948A
- Matthew Oliver Kitching, Olivia E Dixon, Marcus Baumann, Ian Richard Baxendale
- University of Durham, Chemistry, Durham, UK
Read the publication that featured this abstractWe report a series of multi-step flow operations to deliver an advanced hydrazine intermediate used in the assembly of the Neurotensin modulator SR142948A. Several new reactor configurations have enabled chemical transformations that would be otherwise difficult or dangerous to perform at scale. Overall the flow approach has allowed the preparation of kilogram quantities of the required hydrazine via a short and efficient route.
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R-Series
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible |
- Precise |
- Automatable
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
E-Series
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust |
- Easy to use |
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The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.
