Examples of published literature for Electrochemical reactions

Cobalt-electrocatalytic HAT for functionalization of unsaturated C–C bonds

Samer Gnaima, Adriano Bauera, Hai-Jun Zhanga, Longrui Chena, Cara Gannettb, Christian A. Malapitc, David E. Hilld, David Vogtc, Tianhua Tangc, Ryan A. Daleya, Wei Haoa, Rui Zengb, Mathilde Quertenmonte, Wesley D. Beckc, Elya Kandaharid, Julien C. Vantourouta, Pierre-Georges Echeverriae, Hector D. Abrunab, Donna G. Blackmonda, Shelley D. Minteerc, Sarah E. Reismand, Matthew S. Sigmanc & Phil S. Barana

  • aDepartment of Chemistry, The Scripps Research Institute (TSRI), La Jolla, CA, USA
  • bDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA
  • cDepartment of Chemistry, University of Utah, Salt Lake City, UT, USA
  • dThe Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, USA
  • eMinakem Recherche, Beuvry-la-Forêt, France
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Supporting-Electrolyte-Free Anodic Oxidation of Oxamic Acids into Isocyanates: An Expedient Way to Access Ureas, Carbamates, and Thiocarbamates

Alessia Pettia, Corentin Fagnana, Carlo G. W. van Melisa, Nour Tanbouzab, Anthony D. Garciaa, Andrea Mastrodonatoa, Matthew C. Leecha, Iain C. A. Goodalla, Adrian P. Dobbsa, Thierry Ollevierb, Kevin Lam*a

  • aSchool of Science, University of Greenwich, Chatham Maritime, Chatham, Kent ME4 4TB, U.K.
  • bDépartement de Chimie, Université Laval, 1045 avenue de la Médecine, Québec, QC G1V 0A6, Canada
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Flow electrochemistry: a safe tool for fluorine chemistry

Bethan Wintersona, Tim Rennigholtza, Thomas Wirtha

  • aSchool of Chemistry, Cardiff University, Park Place, Main Building, Cardiff, Cymru/Wales, UK
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Flow Electrosynthesis of Sulfoxides, Sulfones, and Sulfoximines without Supporting Electrolytes

Nasser Amri1 and Thomas Wirth1

  • 1School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, United Kingdom
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Accelerating Electrochemical Synthesis through Automated Flow: Efficient Synthesis of Chalcogenophosphites

Nasser Amri, Thomas Wirth*

  • School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK
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Making electrochemistry easily accessible to the synthetic chemist

Christiane Schotten*a, Thomas P. Nichollsa, Richard A. Bourneb, Nikil Kapurc, Bao N. Nguyena, Charlotte E. Willans*a

  • aSchool of Chemistry, University of Leeds, Leeds LS2 9JT, UK.
  • bSchool of Chemical and Process Engineering, University of Leeds, Leeds LS2 9JT, UK
  • cSchool of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, UK
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Automated Electrochemical Selenenylations

Nasser Amri, Thomas Wirth

  • School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK
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Electroorganic Synthesis under Flow Conditions

Mohamed Elsherbini, Thomas Wirth

  • School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, United Kingdom
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Continuous‐Flow Electrochemical Generator of Hypervalent Iodine Reagents: Synthetic Applications

Dr Mohamed Elsherbini, Bethan Winterson, Haifa Alharbi, Ana A. Folgueiras-Amador, Clina Gnot, Thomas Wirth

  • School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff, CF10 3AT UK
View abstract

Flow Electrochemical Cyclizations via Amidyl Radicals: Easy Access to Cyclic Ureas

Nisar Ahmeda,b*, Aggeliki Vgenopouloua

  • a School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK
  • b School of Chemistry, University of Bristol, Bristol, BS8 1TS, UK
View abstract

Efficient Flow Electrochemical Alkoxylation of Pyrrolidine-1-Carbaldehyde

Nasser Amria, Ryan A. Skiltonb, Duncan Guthrieb, Thomas Wirth*a

  • a School of Chemistry, Cardiff University, Park Place, Cardiff, CF10 3AT, UK
  • b Vapourtec Ltd., 21 Park Farm Business Centre, Bury St Edmunds, IP28 6TS, UK
View abstract

Application Notes regarding Electrochemical reactions

Application Note 64: Direct electrochemical oxidation of 4- tert-butyltoluene

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This application note demonstrates the use of the Vapourtec Ion electrochemical reactor for the direct oxidation of 4-tert-butyltoluene into 4-tert-butyl benzaldehyde dimethyl acetal. After optimization of this key reaction, the desired product was afforded in a yield of 88%.

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Application Note 63: Electrochemical pathway for cross coupling of organic halides – Csp2-Csp3 bonding

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We now present a new application note prepared from work undertaken by New Path Molecular Research Ltd.  This research project uses the Vapourtec Ion electrochemical reactor for the reductive cross-electrophile coupling of organic halides, constructing a Csp2-Csp3 bond. After optimization of this key reaction, the desired product was afforded in a yield of 81%.

In 2017, Pfizer revealed a reductive cross coupling reaction to construct Csp2-Csp3 bonds from organic halides in a batch electrochemical system (Perkins, Pedro, & Hansen, 2017). An electrochemical protocol was used to reduce a nickel catalyst (NiII to Ni0 or NiIII to NiII according to literature).  In the application note presented by Vapourtec this same reaction is optimised under continuous flow conditions using the Vapourtec Ion electrochemical reactor.

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