Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata
- Matteo Planchestainera
- Martina Letizia Contenteab
- Jennifer Cassidya
- Francesco Molinarib
- Lucia Tamborini*c
- Francesca Paradisi*ad
- * Corresponding authors
- a UCD School of Chemistry, University College Dublin, Belfield, Dublin 4, Ireland
- b Department of Food, Environmental and Nutritional Sciences (DeFENS), Università degli studi di Milano, Via Mangiagalli 25, Milan, Italy
- c Department of Pharmaceutical Sciences (DISFARM), Università degli studi di Milano, Via Mangiagalli 25, Milan, Italy
- d School of Chemistry, University of Nottingham, University Park, Nottingham, UKRead the publication that featured this abstract
The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminase from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed into the corresponding amines in good to excellent yields. The process was implemented with an integrated in-line purification step for the recovery of the pure amines.
Get in touch
For more information on flow chemistry systems and services please use the contact methods below.
Call us on +44 (0)1284 728659 or Email us
The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible |
- Precise |
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust |
- Easy to use |
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.