Continuous-Flow Accelerated Sulfation of Heparan Sulfate Intermediates
- Saurabh Anand
- Sandhya Mardhekar
- Rakesh Raigawali
- Nirmala Mohanta
- Prashant Jain
- Chethan D. Shanthamurthy
- Boopathy Gnanaprakasam*
- Raghavendra Kikkeri*
- Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pune-411 008, India
Read the publication that featured this abstractWe report for the first time a continuous-flow strategy to execute O-sulfation modification of heparan sulfate (HS) oligosaccharides. A systematic investigation of the influence of the flow parameters on the installation of the sulfate group on glucosamine monosaccharide can aid the development of a comprehensive, quick, and reliable strategy for O-sulfation of HS oligosaccharide precursors. Deprotection of the sulfated heparin intermediates led to the development of a comprehensive biologically inspired oligosaccharide library to understand the crucial structure–function relationship of HS.
Get in touch
For more information on flow chemistry systems and services please use the contact methods below.
Call us on +44 (0)1284 728659 or Email us
Resource Centre
R-Series

The Vapourtec R-Series is, quite simply, unrivalled for flow chemistry
- Flexible |
- Precise |
- Automatable
The R-Series is undoubtedly the most versatile, modular flow chemistry system available today.
E-Series

The Vapourtec E-Series is the perfect introductory system for flow chemistry
- Robust |
- Easy to use |
- Affordable
The E-Series is a robust and affordable, entry level flow chemistry system designed for reliability and ease of use.