Consecutive photochemical reactions enabled by a dual flow reactor coil strategy
- Ruairi Crawforda
- Mara Di Filippoa
- Duncan Guthrieb
- Marcus Baumanna
- aSchool of Chemistry, Science Centre South, University College Dublin, D04 N2E2, Dublin, Ireland
- bVapourtec, Fornham St Genevieve, Bury St Edmunds, Suffolk, IP28 6TS, UKMRead the publication that featured this abstract
The application of a dual reactor coil for consecutive photochemical reactions is presented in continuous flow mode. This strategy enables for the first time the use of a single LED-based light source to perform two distinct photochemical reactions in an uninterrupted fashion. This approach is demonstrated for the telescoped synthesis and functionalisation of drug-like quinolines and compared to alternatives exploiting two photochemical reactor set-ups operated in sequence. The presented strategy enables the intensified exploitation of photochemical reactions in modern synthesis.
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