Consecutive photochemical reactions enabled by a dual flow reactor coil strategy

    • Ruairi Crawforda
    • Mara Di Filippoa
    • Duncan Guthrieb
    • Marcus Baumanna
    • aSchool of Chemistry, Science Centre South, University College Dublin, D04 N2E2, Dublin, Ireland
    • bVapourtec, Fornham St Genevieve, Bury St Edmunds, Suffolk, IP28 6TS, UKM

    The application of a dual reactor coil for consecutive photochemical reactions is presented in continuous flow mode. This strategy enables for the first time the use of a single LED-based light source to perform two distinct photochemical reactions in an uninterrupted fashion. This approach is demonstrated for the telescoped synthesis and functionalisation of drug-like quinolines and compared to alternatives exploiting two photochemical reactor set-ups operated in sequence. The presented strategy enables the intensified exploitation of photochemical reactions in modern synthesis.

    Read the publication that featured this abstract

    Get in touch

    For more information on flow chemistry systems and services please use the contact methods below.

    Call us on +44 (0)1284 728659 or Email us