Compounds and compositions as inhibitors of endosomal toll-like receptors

Inventors: Phillip Alper, Jonathan DEANE, Songchun Jiang, Tao Jiang, Thomas Knoepfel, Pierre-Yves Michellys, Daniel Mutnick, Wei Pei, Peter SYKA, Guobao Zhang, Yi Zhang

• Assignee: Novartis AG, Novartis Institutes for BioMedical Research Inc

The invention disclosed herein relates to 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridinyl compounds and 4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridinyl compounds of Formula (A), pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of autoimmune diseases.

Read the publication that featured this abstract